9G78
CryoEM structure of human rho1 GABAA receptor in complex with neurosteroid pregnanolone
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E (A, B, C, D, E) | Gamma-aminobutyric acid receptor subunit rho-1 | polymer | 479 | 55950.2 | 5 | UniProt (P24046) Pfam (PF02931) Pfam (PF02932) | Homo sapiens (human) | GABA(A) receptor subunit rho-1,GABA(C) receptor |
| 2 | DB, EB, F, FA, G... (E, A, C, D, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 10 | Chemie (NAG) | |||
| 3 | BB, DA, H, PA, Q (D, B, A, C) | Pregnanolone | non-polymer | 318.5 | 5 | Chemie (P9N) | |||
| 4 | CB, EA, FB, HA, I... (E, C, A, D, B) | N-OCTANE | non-polymer | 114.2 | 20 | Chemie (OCT) | |||
| 5 | GB, IA, J, UA, W (E, C, A, D, B) | DODECANE | non-polymer | 170.3 | 5 | Chemie (D12) | |||
| 6 | AA, HB, JA, K, KB... (B, E, C, A, D) | DECANE | non-polymer | 142.3 | 10 | Chemie (D10) | |||
| 7 | AB, BA, CA, LB, MB... (D, B, E, C, A) | HEXANE | non-polymer | 86.2 | 10 | Chemie (HEX) | |||
| 8 | NB, OB, PB, QB, RB (A, B, C, D, E) | water | water | 18.0 | 25 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 279751.2 | |
| Non-Polymers* | Number of molecules | 60 |
| Total formula weight | 9225.4 | |
| All* | Total formula weight | 288976.5 |
