9G74

Mouse mitochondrial DNA polymerase gamma ternary complex in replication conformer

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	DNA polymerase subunit gamma-1	polymer	1199	135078.2	1	UniProt (Q75WC0) Pfam (PF18136) UniProt (by SIFTS) (P54099)	Mus musculus (house mouse)
2	B, C (B, C)	DNA polymerase subunit gamma-2	polymer	450	50778.6	2	UniProt (Q9QZM2) Pfam (PF03129)	Mus musculus (house mouse)	DNA polymerase gamma accessory 55 kDa subunit,p55,Mitochondrial DNA polymerase accessory subunit,MtPolB,PolG-beta
3	D (P)	DNA (primer strand)	polymer	25	7780.0	1		synthetic construct
4	E (T)	DNA (template strand)	polymer	40	12162.8	1		synthetic construct
5	F (A)	CALCIUM ION	non-polymer		40.1	1	Chemie (CA)
6	G (A)	2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE	non-polymer		467.2	1	Chemie (DCP)

Sequence modifications

A: 26 - 1217 (UniProt: Q75WC0)

PDB	External Database	Details
Met 19	-	initiating methionine
His 20	-	expression tag
His 21	-	expression tag
His 22	-	expression tag
His 23	-	expression tag
His 24	-	expression tag
His 25	-	expression tag

B, C: 17 - 459 (UniProt: Q9QZM2)

PDB	External Database	Details
Met 16	-	initiating methionine
His 460	-	expression tag
His 461	-	expression tag
His 462	-	expression tag
His 463	-	expression tag
His 464	-	expression tag
His 465	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	256578.3
Non-Polymers*	Number of molecules	2
	Total formula weight	507.2
All*	Total formula weight	257085.5

*Water molecules are not included.