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9G70

CryoEM structure of human rho1 GABAA receptor in complex with GABA and neurosteroid pregnanolone

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D, E
(A, B, C, D, E)
Gamma-aminobutyric acid receptor subunit rho-1polymer47955950.25UniProt (P24046)
Pfam (PF02931)
Pfam (PF02932)
Homo sapiens (human)GABA(A) receptor subunit rho-1,GABA(C) receptor
2F, HA, IA, O, Y
(A, D, C)
GAMMA-AMINO-BUTANOIC ACIDnon-polymer103.15Chemie (ABU)
3AA, G, H, JA, KA...
(C, A, D, B, E)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.210Chemie (NAG)
4GA, I, QA, R, X
(C, A, D, B)
Pregnanolonenon-polymer318.55Chemie (P9N)
5BA, CA, J, K, LA...
(C, A, D, B, E)
N-OCTANEnon-polymer114.210Chemie (OCT)
6DA, L, NA, U, VA
(C, A, D, B, E)
DECANEnon-polymer142.35Chemie (D10)
7EA, FA, M, N, OA...
(C, A, D, B, E)
HEXANEnon-polymer86.210Chemie (HEX)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains5
Total formula weight279751.2
Non-Polymers*Number of molecules45
Total formula weight7035.6
All*Total formula weight286786.7
*Water molecules are not included.

249697

PDB entries from 2026-02-25

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