9G6I
Crystal structure of S. epidermidis ClpP in complex with bortezomib - cocrystallization
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | ATP-dependent Clp protease proteolytic subunit | polymer | 199 | 22106.0 | 14 | UniProt (A0A0N1MQL5) Pfam (PF00574) UniProt (by SIFTS) (Q5HQW0) | Staphylococcus epidermidis | Endopeptidase Clp |
| 2 | AA, CA, EA, GA, IA... (G, H, I, J, K...) | ACETATE ION | non-polymer | 59.0 | 14 | Chemie (ACT) PubChem (175) | |||
| 3 | BA, DA, FA, HA, JA... (G, H, I, J, K...) | N-[(1R)-1-(DIHYDROXYBORYL)-3-METHYLBUTYL]-N-(PYRAZIN-2-YLCARBONYL)-L-PHENYLALANINAMIDE | non-polymer | 384.2 | 14 | Chemie (BO2) PubChem (387447) | |||
| 4 | AB, BB, CB, DB, QA... (K, L, M, N, A...) | water | water | 18.0 | 1746 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H, I, J, K, L, M, N: 1 - 193 (UniProt: A0A0N1MQL5)
| PDB | External Database | Details |
|---|---|---|
| His 194 | - | expression tag |
| His 195 | - | expression tag |
| His 196 | - | expression tag |
| His 197 | - | expression tag |
| His 198 | - | expression tag |
| His 199 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 14 |
| Total formula weight | 309484.4 | |
| Non-Polymers* | Number of molecules | 28 |
| Total formula weight | 6205.9 | |
| All* | Total formula weight | 315690.3 |
