9G5I

Cryo-EM structure of a 2:1 ALK:ALKAL2 complex obtained after re-processing of EMPIAR-10930 data

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	ALK tyrosine kinase receptor	polymer	379	39377.6	2	UniProt (Q9UM73) Pfam (PF12810)	Homo sapiens (human)	Anaplastic lymphoma kinase
2	C (C)	ALK and LTK ligand 2	polymer	128	14640.0	1	UniProt (Q6UX46) Pfam (PF15129)	Homo sapiens (human)	Augmentor alpha,AUG-alpha

Sequence modifications

A, B: 648 - 1025 (UniProt: Q9UM73)

PDB	External Database	Details
Gly 647	-	expression tag

C: 25 - 152 (UniProt: Q6UX46)

PDB	External Database	Details
Tyr 66	Cys 66	engineered mutation

Sequence viewer

Contents of the asymmetric unit

*Water molecules are not included.