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9G55

CryoEM structure of human rho1 GABAA receptor in complex with neurosteroid THDOC

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D, E
(A, B, C, D, E)
Gamma-aminobutyric acid receptor subunit rho-1polymer47955950.25UniProt (P24046)
Pfam (PF02931)
Pfam (PF02932)
Homo sapiens (human)GABA(A) receptor subunit rho-1,GABA(C) receptor
2CA, DA, F, G, NA...
(C, A, D, B, E)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.210Chemie (NAG)
3AB, EA, H, PA, T
(E, C, A, D, B)
Tetrahydrodeoxycorticosteronenon-polymer334.55Chemie (A8Z)
4BB, CB, DB, FA, FB...
(E, C, A, D, B)
HEXANEnon-polymer86.220Chemie (HEX)
5EB, IA, L, TA, X
(E, C, A, D, B)
DODECANEnon-polymer170.35Chemie (D12)
6BA, GB, KA, MA, N...
(C, E, D, A, B)
DECANEnon-polymer142.310Chemie (D10)
7AA, HB, LA, O, WA
(B, E, C, A, D)
N-OCTANEnon-polymer114.25Chemie (OCT)
8IB, JB, KB, LB, MB
(A, B, C, D, E)
waterwater18.010Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains5
Total formula weight279751.2
Non-Polymers*Number of molecules55
Total formula weight8453.7
All*Total formula weight288204.8
*Water molecules are not included.

247947

PDB entries from 2026-01-21

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