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9G4B

Human KRas4A (GDP) in complex with compound 15

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
GTPase KRaspolymer17219607.11UniProt (P01116)
Pfam (PF00071)
Homo sapiens (human)K-Ras 2,Ki-Ras,c-K-ras,c-Ki-ras
2B
(A)
GUANOSINE-5'-DIPHOSPHATEnon-polymer443.21Chemie (GDP)
3C
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
4D, E, F
(A)
1,2-ETHANEDIOLnon-polymer62.13Chemie (EDO)
5G
(A)
(3Z)-7-chloro-10,21-dihydroxy-2,2-dioxo-18-(4-piperidyl)-2-lambda-6,5-dithia-3,12,18-triazatetracyclo[18.3.1.04,12.06,11]tetracosa-1(23),3,6,8,10,20(24),21-heptaen-19-onenon-polymer551.11Chemie (A1IIU)
6H
(A)
waterwater18.0130Chemie (HOH)
Sequence modifications
A: 1 - 169 (UniProt: P01116)
PDBExternal DatabaseDetails
Gly -2-expression tag
Gly -1-expression tag
Ser 0-expression tag
Ser 118Cys 118engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight19607.1
Non-Polymers*Number of molecules6
Total formula weight1204.8
All*Total formula weight20811.9
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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