9G0V

Human LTC4 synthase in complex with compound 1

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Leukotriene C4 synthase	polymer	157	17468.6	1	UniProt (Q16873) Pfam (PF01124)	Homo sapiens (human)	LTC4 synthase,Glutathione S-transferase LTC4,Leukotriene-C(4) synthase,Leukotriene-C4 synthase
2	B, D (A)	PALMITIC ACID	non-polymer		256.4	2	Chemie (PLM)
3	C (A)	DODECYL-BETA-D-MALTOSIDE	non-polymer		510.6	1	Chemie (LMT)
4	E (A)	[(2~{S})-5-[[(2~{R})-1-(2-hydroxy-2-oxoethylamino)-1-oxidanylidene-3-sulfanyl-propan-2-yl]amino]-1-oxidanyl-1,5-bis(oxidanylidene)pentan-2-yl]azanium	non-polymer		308.3	1	Chemie (VDW)
5	F (A)	1-[3,4-bis(fluoranyl)phenyl]-9-[6-[2,2,2-tris(fluoranyl)ethoxy]pyrimidin-4-yl]-1,9-diazaspiro[5.5]undecan-2-one	non-polymer		456.4	1	Chemie (A1IHO)

Sequence modifications

A: 2 - 150 (UniProt: Q16873)

PDB	External Database	Details
Met -6	-	initiating methionine
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
Gly 1	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	17468.6
Non-Polymers*	Number of molecules	5
	Total formula weight	1788.2
All*	Total formula weight	19256.8

*Water molecules are not included.