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9G09

Structure of human RNF213 bound to the secreted effector IpaH2.5 from Shigella flexneri

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(B)
E3 ubiquitin-protein ligase IpaH2.5polymer56363651.71UniProt (A0A0H2USC0)
Pfam (PF12468)
Pfam (PF14496)
Shigella flexneri 5a str. M90TInvasion plasmid antigen 2.5
2B
(A)
E3 ubiquitin-protein ligase RNF213polymer5247596450.31UniProt (Q63HN8)
Pfam (PF00097)
Pfam (PF20173)
Homo sapiens (human)ALK lymphoma oligomerization partner on chromosome 17,E3 ubiquitin-lipopolysaccharide ligase RNF213,Mysterin,RING finger protein 213
3C
(A)
ADENOSINE-5'-TRIPHOSPHATEnon-polymer507.21Chemie (ATP)
4D
(A)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
5E, F, G
(A)
ZINC IONnon-polymer65.43Chemie (ZN)
Sequence modifications
A: 1 - 5207 (UniProt: Q63HN8)
PDBExternal DatabaseDetails
Met -39-initiating methionine
Ala -38-expression tag
Ser -37-expression tag
Trp -36-expression tag
Ser -35-expression tag
His -34-expression tag
Pro -33-expression tag
Gln -32-expression tag
Phe -31-expression tag
Glu -30-expression tag
Lys -29-expression tag
Gly -28-expression tag
Ser -27-expression tag
Ala -26-expression tag
Gly -25-expression tag
Ser -24-expression tag
Ala -23-expression tag
Ala -22-expression tag
Gly -21-expression tag
Ser -20-expression tag
Gly -19-expression tag
Ala -18-expression tag
Gly -17-expression tag
Trp -16-expression tag
Ser -15-expression tag
His -14-expression tag
Pro -13-expression tag
Gln -12-expression tag
Phe -11-expression tag
Glu -10-expression tag
Lys -9-expression tag
Glu -8-expression tag
Asn -7-expression tag
Leu -6-expression tag
Tyr -5-expression tag
Phe -4-expression tag
Gln -3-expression tag
Ala -2-expression tag
Met -1-expression tag
Ser 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight660101.9
Non-Polymers*Number of molecules5
Total formula weight727.7
All*Total formula weight660829.7
*Water molecules are not included.

249697

PDB entries from 2026-02-25

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