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9FZQ

Proton conductance by human uncoupling protein 1 is inhibited by both purine and pyrimidine nucleotides

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Mitochondrial brown fat uncoupling protein 1polymer31033339.61UniProt (P25874)
Pfam (PF00153)
Homo sapiens (human)UCP 1,Solute carrier family 25 member 7,Thermogenin
2B
(B)
CA9871polymer12413423.81Lama glama
3C
(C)
CA9865polymer12814022.71Lama glama
4D
(A)
URIDINE 5'-TRIPHOSPHATEnon-polymer484.11Chemie (UTP)
5E, F, G
(A)
CARDIOLIPINnon-polymer1464.03Chemie (CDL)
Sequence modifications
A: 2 - 307 (UniProt: P25874)
PDBExternal DatabaseDetails
Thr -2-expression tag
Ser -1-expression tag
Glu 0-expression tag
Asp 1-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight60786.1
Non-Polymers*Number of molecules4
Total formula weight4876.3
All*Total formula weight65662.4
*Water molecules are not included.

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PDB entries from 2025-07-16

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