9FX7

Crystal structure of Cryo2RT SARS-CoV-2 main protease at 294K

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	3C-like proteinase nsp5	polymer	306	33825.5	2	UniProt (P0DTD1) Pfam (PF05409)	Severe acute respiratory syndrome coronavirus 2	3CL-PRO,3CLp,Main protease,Mpro,Non-structural protein 5,nsp5,SARS coronavirus main proteinase
2	C, D, G, H, I (A, B)	DIMETHYL SULFOXIDE	non-polymer		78.1	5	Chemie (DMS)
3	E, J (A, B)	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
4	F, K (A, B)	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
5	L, M (A, B)	water	water		18.0	209	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	67651.1
Non-Polymers*	Number of molecules	9
	Total formula weight	631.4
All*	Total formula weight	68282.5

*Water molecules are not included.