9FWS
Crystal Structure of SARS-CoV-2 NSP10-NSP14 (ExoN) in complex with VT00258
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Non-structural protein 10 | polymer | 131 | 13805.7 | 1 | UniProt (P0DTC1) Pfam (PF09401) | Severe acute respiratory syndrome coronavirus 2 | nsp10,Growth factor-like peptide,GFL |
| 2 | B (B) | Guanine-N7 methyltransferase nsp14 | polymer | 290 | 32753.8 | 1 | UniProt (P0DTD1) Pfam (PF06471) | Severe acute respiratory syndrome coronavirus 2 | Non-structural protein 14,nsp14,Proofreading exoribonuclease nsp14,ExoN |
| 3 | C (A) | 7-METHOXY-1H-INDAZOLE | non-polymer | 148.2 | 1 | Chemie (MI7) | |||
| 4 | D (A) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 5 | E, F, G, H (A, B) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 6 | I, J (A, B) | water | water | 18.0 | 383 | Chemie (HOH) |
Sequence modifications
B: 1 - 289 (UniProt: P0DTD1)
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 46559.5 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 487.9 | |
| All* | Total formula weight | 47047.5 |
