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9FWQ

Crystal Structure of SARS-CoV-2 NSP10-NSP14 (ExoN) in complex with VT00218

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Non-structural protein 10polymer13113805.71UniProt (P0DTC1)
Pfam (PF09401)
Severe acute respiratory syndrome coronavirus 2nsp10,Growth factor-like peptide,GFL
2B
(B)
Guanine-N7 methyltransferase nsp14polymer29032753.81UniProt (P0DTD1)
Pfam (PF06471)
Severe acute respiratory syndrome coronavirus 2Non-structural protein 14,nsp14,Proofreading exoribonuclease nsp14,ExoN
3C, D, F, G
(A, B)
ZINC IONnon-polymer65.44Chemie (ZN)
4E, H
(A, B)
5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyridinenon-polymer123.22Chemie (A1IGJ)
5I
(B)
MAGNESIUM IONnon-polymer24.31Chemie (MG)
6J, K
(A, B)
waterwater18.0154Chemie (HOH)
Sequence modifications
A: 1 - 130 (UniProt: P0DTC1)
PDBExternal DatabaseDetails
Asp 131-expression tag
B: 1 - 289 (UniProt: P0DTD1)
PDBExternal DatabaseDetails
Met 0-initiating methionine
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight46559.5
Non-Polymers*Number of molecules7
Total formula weight532.3
All*Total formula weight47091.8
*Water molecules are not included.

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PDB entries from 2025-07-16

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