9FVP
Crystal structure of 14-3-3 sigma in complex with Tau pS214 peptide and covalent stabilizer JS24
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 14-3-3 protein sigma | polymer | 236 | 26543.0 | 1 | UniProt (P31947) Pfam (PF00244) | Homo sapiens (human) | Epithelial cell marker protein 1,Stratifin |
| 2 | B (P) | Microtubule-associated protein tau | polymer | 13 | 1520.6 | 1 | UniProt (P10636) | Homo sapiens | Neurofibrillary tangle protein,Paired helical filament-tau,PHF-tau |
| 3 | C (A) | 1-(3-bromanyl-4-methyl-phenyl)-2-(4-methylphenyl)imidazole | non-polymer | 327.2 | 1 | Chemie (A1IGF) | |||
| 4 | D, E (A, P) | water | water | 18.0 | 149 | Chemie (HOH) |
Sequence modifications
A: 1 - 231 (UniProt: P31947)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Ala -3 | - | expression tag |
| Met -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Lys 86 | Glu 86 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 28063.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 327.2 | |
| All* | Total formula weight | 28390.8 |
