9FVE
Crystal structure of VcSiaP W73A mutant in complex with sialic acid and a VHH antibody (VHH_VcP#2)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, G, I... (A, C, E, G, I...) | Sialic acid-binding periplasmic protein SiaP | polymer | 303 | 33991.6 | 12 | UniProt (Q9KR64) Pfam (PF03480) | Vicugna pacos (alpaca) | |
| 2 | B, D, F, H, J... (B, D, F, H, J...) | VHH_VcP#2 | polymer | 123 | 13483.9 | 12 | Vicugna pacos (alpaca) | ||
| 3 | AA, CA, EA, FA, GA... (E, G, I, K, M...) | N-acetyl-beta-neuraminic acid | non-polymer | 309.3 | 12 | Chemie (SLB) | |||
| 4 | BA, DA, JA, LA, MA... (E, G, Q, U) | GLYCEROL | non-polymer | 92.1 | 6 | Chemie (GOL) |
Sequence modifications
A, C, E, G, I, K, M, O, Q, U, W, Y: 0 - 299 (UniProt: Q9KR64)
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Ala -2 | - | expression tag |
| Met -1 | - | expression tag |
| Gly 0 | Ala 22 | conflict |
| Ala 73 | Trp 95 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 24 |
| Total formula weight | 569705.6 | |
| Non-Polymers* | Number of molecules | 18 |
| Total formula weight | 4263.8 | |
| All* | Total formula weight | 573969.4 |
