9FVE
Crystal structure of VcSiaP W73A mutant in complex with sialic acid and a VHH antibody (VHH_VcP#2)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, G, I... (A, C, E, G, I...) | Sialic acid-binding periplasmic protein SiaP | polymer | 303 | 33991.6 | 12 | UniProt (Q9KR64) Pfam (PF03480) | Vicugna pacos (alpaca) | |
| 2 | B, D, F, H, J... (B, D, F, H, J...) | VHH_VcP#2 | polymer | 123 | 13483.9 | 12 | Vicugna pacos (alpaca) | ||
| 3 | AA, CA, EA, FA, GA... (E, G, I, K, M...) | N-acetyl-beta-neuraminic acid | non-polymer | 309.3 | 12 | Chemie (SLB) PubChem (16758151) PubChem (17757261) PubChem (20843074) PubChem (1807423) PubChem (906) PubChem (8565) PubChem (24801877) PubChem (26470719) PubChem (26470725) PubChem (36690637) PubChem (40429907) PubChem (40477531) PubChem (40785048) PubChem (42553514) PubChem (42553516) PubChem (42553518) PubChem (42553520) PubChem (44120039) PubChem (44338934) PubChem (45933901) PubChem (49819355) PubChem (26470722) PubChem (163606) PubChem (57859521) PubChem (58341444) PubChem (58545373) PubChem (439197) PubChem (58964108) PubChem (59331136) PubChem (67604154) PubChem (68257483) PubChem (68260278) PubChem (68315779) PubChem (444885) PubChem (445063) PubChem (445727) PubChem (70643192) PubChem (70666785) PubChem (70979316) PubChem (71299579) PubChem (71650744) PubChem (58392620) PubChem (1549084) PubChem (89869240) PubChem (89869500) PubChem (89869501) PubChem (89869502) PubChem (656387) PubChem (5702294) PubChem (6560217) PubChem (7048542) PubChem (5748928) PubChem (7173829) PubChem (92354618) PubChem (6398955) PubChem (93959067) PubChem (94016791) PubChem (95566316) PubChem (96562275) PubChem (102004932) PubChem (6992095) PubChem (102145501) PubChem (117937408) PubChem (7059665) PubChem (7092680) PubChem (7092682) PubChem (7173826) PubChem (7569151) PubChem (122374560) PubChem (124040735) PubChem (10936453) PubChem (124490223) PubChem (11370291) PubChem (11876108) PubChem (11908614) PubChem (145832226) PubChem (13657114) PubChem (15560314) PubChem (15560306) PubChem (15560307) PubChem (15560308) PubChem (15560310) PubChem (15560312) PubChem (15560313) PubChem (15560315) PubChem (15560316) PubChem (15560317) PubChem (168364984) PubChem (126963458) PubChem (129672250) PubChem (130267610) PubChem (130330497) PubChem (132187635) PubChem (133688898) PubChem (134689626) PubChem (134973249) PubChem (135053795) PubChem (135055138) PubChem (139256539) PubChem (155021572) PubChem (156051160) PubChem (160911533) PubChem (160911534) PubChem (164670778) PubChem (166985445) PubChem (168314628) PubChem (168358112) PubChem (168358795) PubChem (168369824) PubChem (168370581) PubChem (168373659) PubChem (168375635) PubChem (173875492) PubChem (173910549) PubChem (173918449) | |||
| 4 | BA, DA, JA, LA, MA... (E, G, Q, U) | GLYCEROL | non-polymer | 92.1 | 6 | Chemie (GOL) PubChem (753) |
Sequence modifications
A, C, E, G, I, K, M, O, Q, U, W, Y: 0 - 299 (UniProt: Q9KR64)
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Ala -2 | - | expression tag |
| Met -1 | - | expression tag |
| Gly 0 | Ala 22 | conflict |
| Ala 73 | Trp 95 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 24 |
| Total formula weight | 569705.6 | |
| Non-Polymers* | Number of molecules | 18 |
| Total formula weight | 4263.8 | |
| All* | Total formula weight | 573969.4 |
