9FT4
Crystal structure of human DYRK1A in complex with ARN25507
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Dual specificity tyrosine-phosphorylation-regulated kinase 1A | polymer | 361 | 42017.4 | 1 | UniProt (Q13627) Pfam (PF00069) | Homo sapiens (human) | Dual specificity YAK1-related kinase,HP86,Protein kinase minibrain homolog,MNBH,hMNB |
| 2 | B (A) | ~{N}4-(5-cyclopropyl-1~{H}-pyrazol-3-yl)-~{N}2-(phenylmethyl)furo[3,2-d]pyrimidine-2,4-diamine | non-polymer | 346.4 | 1 | Chemie (A1IFJ) |
Sequence modifications
A: 127 - 485 (UniProt: Q13627)
| PDB | External Database | Details |
|---|---|---|
| Gly 125 | - | expression tag |
| Pro 126 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 42017.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 346.4 | |
| All* | Total formula weight | 42363.8 |
