9FST
Yeast 20S proteasome with human beta1i (1-51) in complex with epoxyketone inhibitor LU-001i
This is a non-PDB format compatible entry.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, O | Proteasome subunit alpha type-2 | polymer | 250 | 27191.8 | 2 | UniProt (P23639) In PDB | Saccharomyces cerevisiae (brewer's yeast) | Macropain subunit Y7,Multicatalytic endopeptidase complex subunit Y7,Proteasome component Y7,Proteinase YSCE subunit 7 |
2 | B, P | Proteasome subunit alpha type-3 | polymer | 258 | 28748.2 | 2 | UniProt (P23638) In PDB | Saccharomyces cerevisiae (brewer's yeast) | Macropain subunit Y13,Multicatalytic endopeptidase complex subunit Y13,Proteasome component Y13,Proteinase YSCE subunit 13 |
3 | C, Q | Proteasome subunit alpha type-4 | polymer | 254 | 28478.1 | 2 | UniProt (P40303) In PDB | Saccharomyces cerevisiae (brewer's yeast) | Macropain subunit PRE6,Multicatalytic endopeptidase complex subunit PRE6,Proteasome component PRE6,Proteinase YSCE subunit PRE6 |
4 | D, R | Proteasome subunit alpha type-5 | polymer | 260 | 28649.1 | 2 | UniProt (P32379) In PDB | Saccharomyces cerevisiae (brewer's yeast) | Macropain subunit PUP2,Multicatalytic endopeptidase complex subunit PUP2,Proteasome component PUP2,Proteinase YSCE subunit PUP2 |
5 | E, S | Proteasome subunit alpha type-6 | polymer | 234 | 25634.0 | 2 | UniProt (P40302) In PDB | Saccharomyces cerevisiae (brewer's yeast) | Macropain subunit PRE5,Multicatalytic endopeptidase complex subunit PRE5,Proteasome component PRE5,Proteinase YSCE subunit PRE5 |
6 | F, T | Probable proteasome subunit alpha type-7 | polymer | 288 | 31575.1 | 2 | UniProt (P21242) In PDB | Saccharomyces cerevisiae (brewer's yeast) | Macropain subunit C1,Multicatalytic endopeptidase complex subunit C1,Proteasome component C1,Proteinase YSCE subunit 1 |
7 | G, U | Proteasome subunit alpha type-1 | polymer | 252 | 28033.8 | 2 | UniProt (P21243) In PDB | Saccharomyces cerevisiae (brewer's yeast) | Macropain subunit C7-alpha,Multicatalytic endopeptidase complex C7,Proteasome component C7-alpha,Proteasome component Y8,Proteinase YSCE subunit 7,SCL1 suppressor protein |
8 | H, V | Proteasome subunit beta type-2 | polymer | 232 | 25114.5 | 2 | UniProt (P25043) In PDB | Saccharomyces cerevisiae (brewer's yeast) | Macropain subunit PUP1,Multicatalytic endopeptidase complex subunit PUP1,Proteasome component PUP1,Proteinase YSCE subunit PUP1 |
9 | I, W | Proteasome subunit beta type-3 | polymer | 205 | 22627.8 | 2 | UniProt (P25451) In PDB | Saccharomyces cerevisiae (brewer's yeast) | Macropain subunit PUP3,Multicatalytic endopeptidase complex subunit PUP3,Proteasome component PUP3 |
10 | J, X | Proteasome subunit beta type-4 | polymer | 198 | 22545.7 | 2 | UniProt (P22141) In PDB | Saccharomyces cerevisiae (brewer's yeast) | Macropain subunit C11,Multicatalytic endopeptidase complex subunit C11,Proteasome component C11,Proteinase YSCE subunit 11 |
11 | K, Y | Proteasome subunit beta type-5 | polymer | 211 | 23224.1 | 2 | UniProt (P30656) In PDB | Saccharomyces cerevisiae (brewer's yeast) | Macropain subunit PRE2,Multicatalytic endopeptidase complex subunit PRE2,Proteasome component PRE2,Proteinase YSCE subunit PRE2 |
12 | L, Z | Proteasome subunit beta type-6 | polymer | 222 | 24883.9 | 2 | UniProt (P23724) In PDB | Saccharomyces cerevisiae (brewer's yeast) | Multicatalytic endopeptidase complex subunit C5,Proteasome component C5 |
13 | M, a | Proteasome subunit beta type-7 | polymer | 246 | 27200.9 | 2 | UniProt (P30657) In PDB | Saccharomyces cerevisiae (brewer's yeast) | Macropain subunit PRE4,Multicatalytic endopeptidase complex subunit PRE4,Proteasome component PRE4,Proteinase YSCE subunit PRE4 |
14 | N, b | Proteasome subunit beta type-9,Proteasome subunit beta type-1 | polymer | 195 | 21268.8 | 2 | UniProt (P28065) UniProt (P38624) In PDB | Homo sapiens (human) | Low molecular mass protein 2,Macropain chain 7,Multicatalytic endopeptidase complex chain 7,Proteasome chain 7,Proteasome subunit beta-1i,Really interesting new gene 12 protein,Macropain subunit PRE3,Multicatalytic endopeptidase complex subunit PRE3,Proteasome component PRE3,Proteinase YSCE subunit PRE3 |
15 | G, H, U, V | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
16 | G, I, K, N, W... | MAGNESIUM ION | non-polymer | 24.3 | 8 | Chemie (MG) | |||
17 | K, N, Y, b | azanylidene-[2-[[(2S)-1-[(2S)-2-[[(2S)-1-[[(1S)-2-cyclohexyl-1-[(2R,3S,6R,7S)-3-methanoyl-2,6-dimethyl-6,7-bis(oxidanyl)-1,4-oxazepan-7-yl]ethyl]amino]-1-oxidanylidene-hexan-2-yl]carbamoyl]-4,4-bis(fluoranyl)pyrrolidin-1-yl]-1-oxidanylidene-propan-2-yl]amino]-2-oxidanylidene-ethyl]imino-azanium | non-polymer | 715.8 | 4 | Chemie (A1IF8) | |||
18 | K, M, Y, a | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 4 | Chemie (MES) | |||
19 | N | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
20 | water | water | 18.0 | 271 | Chemie (HOH) |
Sequence modifications
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 28 |
Total formula weight | 730351.9 | |
Non-Polymers* | Number of molecules | 21 |
Total formula weight | 4076.5 | |
All* | Total formula weight | 734428.4 |