9FS1
Mutant S1538L of the dihydroorotase domain of human CAD protein bound to carbamoyl aspartate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Multifunctional protein CAD | polymer | 362 | 39648.4 | 1 | UniProt (P27708) Pfam (PF01979) | Homo sapiens (human) | Carbamoyl phosphate synthetase 2-aspartate transcarbamylase-dihydroorotase |
| 2 | B (A) | N-CARBAMOYL-L-ASPARTATE | non-polymer | 176.1 | 1 | Chemie (NCD) | |||
| 3 | C, D, F, H (A) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 4 | E, G (A) | FORMIC ACID | non-polymer | 46.0 | 2 | Chemie (FMT) | |||
| 5 | I (A) | water | water | 18.0 | 425 | Chemie (HOH) |
Sequence modifications
A: 1461 - 1821 (UniProt: P27708)
| PDB | External Database | Details |
|---|---|---|
| Gly 1460 | - | expression tag |
| Leu 1538 | Ser 1538 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 39648.4 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 529.8 | |
| All* | Total formula weight | 40178.2 |
