9FQV
Cryo-EM structure of MmCAT1 bound with FrMLV-RBD in the lysine-bound inward-occluded state
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | High affinity cationic amino acid transporter 1,Green fluorescent protein | polymer | 902 | 98703.8 | 1 | UniProt (Q09143) UniProt (P42212) Pfam (PF13520) Pfam (PF13906) | Mus musculus (house mouse) | CAT-1,CAT1,Ecotropic retroviral leukemia receptor,Ecotropic retrovirus receptor,ERR,EcoR,Solute carrier family 7 member 1,System Y+ basic amino acid transporter |
| 2 | B (B) | Surface protein | polymer | 276 | 30272.1 | 1 | UniProt (P03390) | Murine leukemia virus | SU,Glycoprotein 70,gp70 |
| 3 | C (D) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 894.8 | 1 | In PDB GlyTouCan (G42466VF) | |||
| 4 | D, E (I, C) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 5 | F (A) | LYSINE | non-polymer | 147.2 | 1 | Chemie (LYS) PubChem (641599) PubChem (4477687) | |||
| 6 | G, H (A) | CHOLESTEROL HEMISUCCINATE | non-polymer | 486.7 | 2 | Chemie (Y01) PubChem (16219150) PubChem (22210610) PubChem (57163942) PubChem (45489984) PubChem (89891013) PubChem (99567468) PubChem (124427194) PubChem (124897021) PubChem (124897020) PubChem (10005657) PubChem (130340716) PubChem (11969853) PubChem (137392566) PubChem (137496323) PubChem (155804219) PubChem (169132514) PubChem (60078761) PubChem (73440805) PubChem (99567469) PubChem (65082) PubChem (124301053) PubChem (124302591) PubChem (363416) PubChem (124303794) PubChem (124421343) PubChem (124427195) PubChem (500055) PubChem (124914595) PubChem (124914596) PubChem (13301926) PubChem (13301927) PubChem (131705526) PubChem (137332121) PubChem (137496357) PubChem (146157332) PubChem (154929912) PubChem (155199678) PubChem (156327905) PubChem (156426247) PubChem (156516588) PubChem (166979870) PubChem (167024614) PubChem (169132513) PubChem (170117245) PubChem (172400028) |
Sequence modifications
A: 13 - 622 (UniProt: Q09143)
A: 635 - 871 (UniProt: P42212)
B: 35 - 270 (UniProt: P03390)
| PDB | External Database | Details |
|---|---|---|
| Ala 623 | - | linker |
| Glu 624 | - | linker |
| Asn 625 | - | linker |
| Leu 626 | - | linker |
| Tyr 627 | - | linker |
| Phe 628 | - | linker |
| Gln 629 | - | linker |
| Ser 630 | - | linker |
| Gly 631 | - | linker |
| Ser 632 | - | linker |
| Ala 633 | - | linker |
| Val 634 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Leu 697 | Phe 64 | conflict |
| Thr 698 | Ser 65 | conflict |
| Lys 839 | Ala 206 | conflict |
| Leu 864 | His 231 | conflict |
| Ser 872 | - | expression tag |
| Gly 873 | - | expression tag |
| Leu 874 | - | expression tag |
| Arg 875 | - | expression tag |
| Ser 876 | - | expression tag |
| Trp 877 | - | expression tag |
| Ser 878 | - | expression tag |
| His 879 | - | expression tag |
| Pro 880 | - | expression tag |
| Gln 881 | - | expression tag |
| Phe 882 | - | expression tag |
| Glu 883 | - | expression tag |
| Lys 884 | - | expression tag |
| Gly 885 | - | expression tag |
| Gly 886 | - | expression tag |
| Gly 887 | - | expression tag |
| Ser 888 | - | expression tag |
| Gly 889 | - | expression tag |
| Gly 890 | - | expression tag |
| Gly 891 | - | expression tag |
| Ser 892 | - | expression tag |
| Gly 893 | - | expression tag |
| Gly 894 | - | expression tag |
| Ser 895 | - | expression tag |
| Ala 896 | - | expression tag |
| Trp 897 | - | expression tag |
| Ser 898 | - | expression tag |
| His 899 | - | expression tag |
| Pro 900 | - | expression tag |
| Gln 901 | - | expression tag |
| Phe 902 | - | expression tag |
| Glu 903 | - | expression tag |
| Lys 904 | - | expression tag |
| His 905 | - | expression tag |
| His 906 | - | expression tag |
| His 907 | - | expression tag |
| His 908 | - | expression tag |
| His 909 | - | expression tag |
| His 910 | - | expression tag |
| His 911 | - | expression tag |
| His 912 | - | expression tag |
| His 913 | - | expression tag |
| His 914 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met 4 | - | initiating methionine |
| Gly 5 | - | expression tag |
| Ile 6 | - | expression tag |
| Leu 7 | - | expression tag |
| Pro 8 | - | expression tag |
| Ser 9 | - | expression tag |
| Pro 10 | - | expression tag |
| Gly 11 | - | expression tag |
| Met 12 | - | expression tag |
| Pro 13 | - | expression tag |
| Ala 14 | - | expression tag |
| Leu 15 | - | expression tag |
| Leu 16 | - | expression tag |
| Ser 17 | - | expression tag |
| Leu 18 | - | expression tag |
| Val 19 | - | expression tag |
| Ser 20 | - | expression tag |
| Leu 21 | - | expression tag |
| Leu 22 | - | expression tag |
| Ser 23 | - | expression tag |
| Val 24 | - | expression tag |
| Leu 25 | - | expression tag |
| Leu 26 | - | expression tag |
| Met 27 | - | expression tag |
| Gly 28 | - | expression tag |
| Cys 29 | - | expression tag |
| Val 30 | - | expression tag |
| Ala 31 | - | expression tag |
| Glu 32 | - | expression tag |
| Thr 33 | - | expression tag |
| Gly 34 | - | expression tag |
| Gly 271 | - | expression tag |
| Thr 272 | - | expression tag |
| Lys 273 | - | expression tag |
| His 274 | - | expression tag |
| His 275 | - | expression tag |
| His 276 | - | expression tag |
| His 277 | - | expression tag |
| His 278 | - | expression tag |
| His 279 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 128975.8 | |
| Branched | Number of molecules | 3 |
| Total formula weight | 1743.6 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1120.6 | |
| All* | Total formula weight | 131840.1 |
