9FQT
Cryo-EM structure of MmCAT1 bound with FrMLV-RBD in the apo inward-open state
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | High affinity cationic amino acid transporter 1,Green fluorescent protein | polymer | 902 | 98703.8 | 1 | UniProt (Q09143) UniProt (P42212) Pfam (PF13520) Pfam (PF13906) | Mus musculus (house mouse) | CAT-1,CAT1,Ecotropic retroviral leukemia receptor,Ecotropic retrovirus receptor,ERR,EcoR,Solute carrier family 7 member 1,System Y+ basic amino acid transporter |
| 2 | B (B) | Surface protein | polymer | 276 | 30272.1 | 1 | UniProt (P03390) | Murine leukemia virus | SU,Glycoprotein 70,gp70 |
| 3 | C (D) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 894.8 | 1 | In PDB GlyTouCan (G42466VF) | |||
| 4 | D, E (I, C) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 5 | F (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 6 | G (A) | CHOLESTEROL HEMISUCCINATE | non-polymer | 486.7 | 1 | Chemie (Y01) PubChem (16219150) PubChem (22210610) PubChem (65082) PubChem (363416) PubChem (45489984) PubChem (500055) PubChem (60078761) PubChem (57163942) PubChem (73440805) PubChem (89891013) PubChem (13301926) PubChem (13301927) PubChem (99567469) PubChem (99567468) PubChem (124427194) PubChem (124897021) PubChem (124897020) PubChem (10005657) PubChem (130340716) PubChem (11969853) PubChem (124301053) PubChem (124302591) PubChem (124303794) PubChem (124421343) PubChem (124427195) PubChem (137392566) PubChem (137496323) PubChem (124914595) PubChem (124914596) PubChem (131705526) PubChem (155804219) PubChem (137332121) PubChem (137496357) PubChem (146157332) PubChem (169132514) PubChem (154929912) PubChem (155199678) PubChem (156327905) PubChem (156426247) PubChem (156516588) PubChem (166979870) PubChem (167024614) PubChem (169132513) PubChem (170117245) PubChem (172400028) |
Sequence modifications
A: 13 - 622 (UniProt: Q09143)
A: 635 - 871 (UniProt: P42212)
B: 1 - 236 (UniProt: P03390)
| PDB | External Database | Details |
|---|---|---|
| Ala 623 | - | linker |
| Glu 624 | - | linker |
| Asn 625 | - | linker |
| Leu 626 | - | linker |
| Tyr 627 | - | linker |
| Phe 628 | - | linker |
| Gln 629 | - | linker |
| Ser 630 | - | linker |
| Gly 631 | - | linker |
| Ser 632 | - | linker |
| Ala 633 | - | linker |
| Val 634 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Leu 697 | Phe 64 | conflict |
| Thr 698 | Ser 65 | conflict |
| Lys 839 | Ala 206 | conflict |
| Leu 864 | His 231 | conflict |
| Ser 872 | - | expression tag |
| Gly 873 | - | expression tag |
| Leu 874 | - | expression tag |
| Arg 875 | - | expression tag |
| Ser 876 | - | expression tag |
| Trp 877 | - | expression tag |
| Ser 878 | - | expression tag |
| His 879 | - | expression tag |
| Pro 880 | - | expression tag |
| Gln 881 | - | expression tag |
| Phe 882 | - | expression tag |
| Glu 883 | - | expression tag |
| Lys 884 | - | expression tag |
| Gly 885 | - | expression tag |
| Gly 886 | - | expression tag |
| Gly 887 | - | expression tag |
| Ser 888 | - | expression tag |
| Gly 889 | - | expression tag |
| Gly 890 | - | expression tag |
| Gly 891 | - | expression tag |
| Ser 892 | - | expression tag |
| Gly 893 | - | expression tag |
| Gly 894 | - | expression tag |
| Ser 895 | - | expression tag |
| Ala 896 | - | expression tag |
| Trp 897 | - | expression tag |
| Ser 898 | - | expression tag |
| His 899 | - | expression tag |
| Pro 900 | - | expression tag |
| Gln 901 | - | expression tag |
| Phe 902 | - | expression tag |
| Glu 903 | - | expression tag |
| Lys 904 | - | expression tag |
| His 905 | - | expression tag |
| His 906 | - | expression tag |
| His 907 | - | expression tag |
| His 908 | - | expression tag |
| His 909 | - | expression tag |
| His 910 | - | expression tag |
| His 911 | - | expression tag |
| His 912 | - | expression tag |
| His 913 | - | expression tag |
| His 914 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met -30 | - | initiating methionine |
| Gly -29 | - | expression tag |
| Ile -28 | - | expression tag |
| Leu -27 | - | expression tag |
| Pro -26 | - | expression tag |
| Ser -25 | - | expression tag |
| Pro -24 | - | expression tag |
| Gly -23 | - | expression tag |
| Met -22 | - | expression tag |
| Pro -21 | - | expression tag |
| Ala -20 | - | expression tag |
| Leu -19 | - | expression tag |
| Leu -18 | - | expression tag |
| Ser -17 | - | expression tag |
| Leu -16 | - | expression tag |
| Val -15 | - | expression tag |
| Ser -14 | - | expression tag |
| Leu -13 | - | expression tag |
| Leu -12 | - | expression tag |
| Ser -11 | - | expression tag |
| Val -10 | - | expression tag |
| Leu -9 | - | expression tag |
| Leu -8 | - | expression tag |
| Met -7 | - | expression tag |
| Gly -6 | - | expression tag |
| Cys -5 | - | expression tag |
| Val -4 | - | expression tag |
| Ala -3 | - | expression tag |
| Glu -2 | - | expression tag |
| Thr -1 | - | expression tag |
| Gly 0 | - | expression tag |
| Gly 237 | - | expression tag |
| Thr 238 | - | expression tag |
| Lys 239 | - | expression tag |
| His 240 | - | expression tag |
| His 241 | - | expression tag |
| His 242 | - | expression tag |
| His 243 | - | expression tag |
| His 244 | - | expression tag |
| His 245 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 128975.8 | |
| Branched | Number of molecules | 3 |
| Total formula weight | 1743.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 707.9 | |
| All* | Total formula weight | 131427.4 |
