9FQL
Crystal structure of hDM2 in complex with a peptidic ligand containing a di-urea insert.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, E, F, I... (A, B, E, F, I...) | E3 ubiquitin-protein ligase Mdm2 | polymer | 86 | 10116.0 | 6 | UniProt (Q00987) | Homo sapiens (human) | Double minute 2 protein,Hdm2,Oncoprotein Mdm2,RING-type E3 ubiquitin transferase Mdm2,p53-binding protein Mdm2 |
| 2 | C, D, G, H, K... (C, D, G, H, K...) | p25Lp26A | polymer | 11 | 1313.5 | 6 | synthetic construct | ||
| 3 | M, N, O, P, Q... (A, B, C, D, I...) | PHOSPHATE ION | non-polymer | 95.0 | 10 | Chemie (PO4) | |||
| 4 | AA, BA, CA, DA, EA... (E, F, G, H, I...) | water | water | 18.0 | 169 | Chemie (HOH) |
Sequence modifications
A, B, E, F, I, J: 25 - 110 (UniProt: Q00987)
| PDB | External Database | Details |
|---|---|---|
| Ala 88 | Val 88 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 68576.5 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 949.7 | |
| All* | Total formula weight | 69526.2 |
