9FQ3

HEV ORF2 protein in complex with Fabs Es1.114 and Es5.127

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Secreted protein ORF2	polymer	486	52886.7	2	UniProt (Q9YLQ9) Pfam (PF03014) Pfam (PF20751) Pfam (PF20752)	Hepatitis E virus	ORF2s
2	C, E (C, E)	human IgG antibody Es5.127 - Fab heavy chain	polymer	240	25675.8	2		Homo sapiens
3	D, F (D, F)	Human IgG antibody Es5.127 - Fab light chain	polymer	216	22762.2	2		Homo sapiens
4	G, I (G, I)	Human IgG antibody Es1.114 - Fab heavy chain	polymer	237	25456.4	2		Homo sapiens
5	H, J (H, J)	Himan IgG antibody Es1.114 - Fab light chain	polymer	206	22467.0	2		Homo sapiens

Sequence modifications

A, B: 126 - 601 (UniProt: Q9YLQ9)

PDB	External Database	Details
Thr 356	Ala 356	conflict
Phe 500	Leu 500	conflict
Ser 551	Gly 551	conflict
His 602	-	expression tag
His 603	-	expression tag
His 604	-	expression tag
His 605	-	expression tag
His 606	-	expression tag
His 607	-	expression tag
His 608	-	expression tag
His 609	-	expression tag
His 610	-	expression tag
His 611	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	10
	Total formula weight	298496.1
All*	Total formula weight	298496.1

*Water molecules are not included.