9FPD
Crystal structure of human TAK1/TAB1 fusion protein in complex with compound S1
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Mitogen-activated protein kinase kinase kinase 7,TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 | polymer | 316 | 35812.1 | 1 | UniProt (O43318) UniProt (Q15750) Pfam (PF07714) | Homo sapiens (human) | Transforming growth factor-beta-activated kinase 1,TGF-beta-activated kinase 1,Mitogen-activated protein kinase kinase kinase 7-interacting protein 1,TGF-beta-activated kinase 1-binding protein 1,TAK1-binding protein 1 |
| 2 | B (A) | 6-[5-[6-(4-oxidanylcyclohexyl)oxy-1~{H}-pyrrolo[2,3-b]pyridin-5-yl]-1,2-oxazol-3-yl]pyridine-2-carboxamide | non-polymer | 419.4 | 1 | Chemie (A1IED) | |||
| 3 | C, D, E (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 4 | F (A) | water | water | 18.0 | 32 | Chemie (HOH) |
Sequence modifications
A: 31 - 303 (UniProt: O43318)
A: 468 - 504 (UniProt: Q15750)
| PDB | External Database | Details |
|---|---|---|
| Met 25 | - | initiating methionine |
| Gly 26 | - | expression tag |
| Ser 27 | - | expression tag |
| Leu 28 | - | expression tag |
| His 29 | - | expression tag |
| Met 30 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 35812.1 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 605.6 | |
| All* | Total formula weight | 36417.7 |
