9FOH
Crystal structure of human IDO1 in complex with iDeg-2
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Indoleamine 2,3-dioxygenase 1 | polymer | 404 | 45367.2 | 1 | UniProt (P14902) Pfam (PF01231) | Homo sapiens (human) | IDO-1,Indoleamine-pyrrole 2,3-dioxygenase |
| 2 | B, C, H (A) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 3 | Chemie (PG4) | |||
| 3 | D (A) | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 1 | Chemie (PGE) | |||
| 4 | E, F, I, J (A) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 4 | Chemie (DMS) | |||
| 5 | G (A) | ((3aS,4R,6R,7aS)-2-((4-(tert-butyl)phenyl)sulfonyl)-5,5-dimethyloctahydro-3aH-4,6-methanoisoindol-3a-yl)methyl (4-iodophenyl)carbamate | non-polymer | 636.6 | 1 | Chemie (A1IEE) | |||
| 6 | K (A) | water | water | 18.0 | 243 | Chemie (HOH) |
Sequence modifications
A: 5 - 400 (UniProt: P14902)
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Pro -2 | - | expression tag |
| Leu -1 | - | expression tag |
| Gly 0 | - | expression tag |
| Ser 1 | - | expression tag |
| Gly 2 | - | expression tag |
| Ile 3 | - | expression tag |
| Gln 4 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 45367.2 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1682.0 | |
| All* | Total formula weight | 47049.1 |
