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9FMU

Cryo-EM structure of human CD163 SRCR1-9 in complex with haptoglobin-hemoglobin

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Hemopressinpolymer14215281.51UniProt (P69905)
Pfam (PF00042)
Homo sapiens (human)
2B
(B)
Spinorphinpolymer14716021.41UniProt (P68871)
Pfam (PF00042)
Homo sapiens (human)
3C
(C)
Isoform 2 of Haptoglobinpolymer34738497.71UniProt (P00738)
Pfam (PF00089)
Homo sapiens (human)Zonulin
4D, E
(D, E)
Scavenger receptor cysteine-rich type 1 protein M130polymer1036112299.82UniProt (Q86VB7)
Pfam (PF00530)
Homo sapiens (human)Hemoglobin scavenger receptor
5F, G
(A, B)
PROTOPORPHYRIN IX CONTAINING FEnon-polymer616.52Chemie (HEM)
6H, I, L, M, O
(C, D, E)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.25Chemie (NAG)
7J, K, N
(D, E)
CALCIUM IONnon-polymer40.13Chemie (CA)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains5
Total formula weight294400.3
Non-Polymers*Number of molecules10
Total formula weight2459.2
All*Total formula weight296859.5
*Water molecules are not included.

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PDB entries from 2025-06-11

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