9FMM
Structure of human ACE2 in complex with a fluorinated small molecule inhibitor
This is a non-PDB format compatible entry.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Angiotensin-converting enzyme 2 | polymer | 730 | 84658.4 | 2 | UniProt (Q9BYF1) Pfam (PF01401) Pfam (PF16959) In PDB | Homo sapiens (human) | Angiotensin-converting enzyme homolog,ACEH,Angiotensin-converting enzyme-related carboxypeptidase,ACE-related carboxypeptidase,Metalloprotease MPROT15 |
2 | A, B | (2~{S})-2-[[(2~{S})-3-[3-[(3-chloranyl-5-fluoranyl-phenyl)methyl]imidazol-4-yl]-1-oxidanyl-1-oxidanylidene-propan-2-yl]amino]-4-methyl-pentanoic acid | non-polymer | 411.9 | 2 | Chemie (A1IDX) | |||
3 | A, B | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 6 | Chemie (NAG) | |||
4 | A, B | 1,2-ETHANEDIOL | non-polymer | 62.1 | 9 | Chemie (EDO) | |||
5 | A, B | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) | |||
6 | A, B | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
7 | A, B | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
8 | water | water | 18.0 | 152 | Chemie (HOH) |
Sequence modifications
A, B: 19 - 740 (UniProt: Q9BYF1)
PDB | External Database | Details |
---|---|---|
His 741 | - | expression tag |
His 742 | - | expression tag |
His 743 | - | expression tag |
His 744 | - | expression tag |
His 745 | - | expression tag |
His 746 | - | expression tag |
His 747 | - | expression tag |
His 748 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 169316.9 | |
Non-Polymers* | Number of molecules | 24 |
Total formula weight | 2992.7 | |
All* | Total formula weight | 172309.6 |