9FM2
Cryo-EM structure of Influenza B/Washington/02/2019 virus neuraminidase in complex with single-domain antibody hVHH-525.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Single-domain antibody hVHH-525 | polymer | 120 | 13094.4 | 1 | Lama glama | ||
| 2 | B, C, D, E (B, C, D, E) | Neuraminidase | polymer | 485 | 53541.0 | 4 | UniProt (A0A5J6DRQ4) Pfam (PF00064) UniProt (by SIFTS) (A0A5Q0MEI0) | Influenza B virus | |
| 3 | F, G, H, I (B, C, D, E) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) |
Sequence modifications
B, C, D, E: 70 - 466 (UniProt: A0A5J6DRQ4)
| PDB | External Database | Details |
|---|---|---|
| Met -18 | - | initiating methionine |
| Pro -17 | - | expression tag |
| Met -16 | - | expression tag |
| Gly -15 | - | expression tag |
| Ser -14 | - | expression tag |
| Leu -13 | - | expression tag |
| Gln -12 | - | expression tag |
| Pro -11 | - | expression tag |
| Leu -10 | - | expression tag |
| Ala -9 | - | expression tag |
| Thr -8 | - | expression tag |
| Leu -7 | - | expression tag |
| Tyr -6 | - | expression tag |
| Leu -5 | - | expression tag |
| Leu -4 | - | expression tag |
| Gly -3 | - | expression tag |
| Met -2 | - | expression tag |
| Leu -1 | - | expression tag |
| Val 0 | - | expression tag |
| Ala 1 | - | expression tag |
| Ser 2 | - | expression tag |
| Val 3 | - | expression tag |
| Leu 4 | - | expression tag |
| Ser 5 | - | expression tag |
| Ala 6 | - | expression tag |
| Trp 7 | - | expression tag |
| Ser 8 | - | expression tag |
| His 9 | - | expression tag |
| Pro 10 | - | expression tag |
| Gln 11 | - | expression tag |
| Phe 12 | - | expression tag |
| Glu 13 | - | expression tag |
| Lys 14 | - | expression tag |
| Gly 15 | - | expression tag |
| Ser 16 | - | expression tag |
| Gly 17 | - | expression tag |
| Ile 18 | - | expression tag |
| Ile 19 | - | expression tag |
| Asn 20 | - | expression tag |
| Glu 21 | - | expression tag |
| Thr 22 | - | expression tag |
| Ala 23 | - | expression tag |
| Asp 24 | - | expression tag |
| Asp 25 | - | expression tag |
| Ile 26 | - | expression tag |
| Val 27 | - | expression tag |
| Tyr 28 | - | expression tag |
| Arg 29 | - | expression tag |
| Leu 30 | - | expression tag |
| Thr 31 | - | expression tag |
| Val 32 | - | expression tag |
| Ile 33 | - | expression tag |
| Ile 34 | - | expression tag |
| Asp 35 | - | expression tag |
| Asp 36 | - | expression tag |
| Arg 37 | - | expression tag |
| Tyr 38 | - | expression tag |
| Glu 39 | - | expression tag |
| Ser 40 | - | expression tag |
| Leu 41 | - | expression tag |
| Lys 42 | - | expression tag |
| Asn 43 | - | expression tag |
| Leu 44 | - | expression tag |
| Ile 45 | - | expression tag |
| Thr 46 | - | expression tag |
| Leu 47 | - | expression tag |
| Arg 48 | - | expression tag |
| Ala 49 | - | expression tag |
| Asp 50 | - | expression tag |
| Arg 51 | - | expression tag |
| Leu 52 | - | expression tag |
| Glu 53 | - | expression tag |
| Met 54 | - | expression tag |
| Ile 55 | - | expression tag |
| Ile 56 | - | expression tag |
| Asn 57 | - | expression tag |
| Asp 58 | - | expression tag |
| Asn 59 | - | expression tag |
| Val 60 | - | expression tag |
| Ser 61 | - | expression tag |
| Thr 62 | - | expression tag |
| Ile 63 | - | expression tag |
| Leu 64 | - | expression tag |
| Ala 65 | - | expression tag |
| Ser 66 | - | expression tag |
| Ile 67 | - | expression tag |
| Gly 68 | - | expression tag |
| Ser 69 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 227258.3 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 884.8 | |
| All* | Total formula weight | 228143.2 |
