9FLT
Crystal structure of human Haspin (GSG2) kinase bound to chemical probe MU1920
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Serine/threonine-protein kinase haspin | polymer | 336 | 38239.8 | 1 | UniProt (Q8TF76) Pfam (PF12330) | Homo sapiens (human) | Germ cell-specific gene 2 protein,H-haspin,Haploid germ cell-specific nuclear protein kinase |
| 2 | B (A) | ~{N}-(1,4-dimethylpyrazol-3-yl)-3-pyridin-4-yl-thieno[3,2-b]pyridin-5-amine | non-polymer | 321.4 | 1 | Chemie (A1IDF) | |||
| 3 | C (A) | NICKEL (II) ION | non-polymer | 58.7 | 1 | Chemie (NI) | |||
| 4 | D (A) | water | water | 18.0 | 66 | Chemie (HOH) |
Sequence modifications
A: 465 - 798 (UniProt: Q8TF76)
| PDB | External Database | Details |
|---|---|---|
| Ser 463 | - | expression tag |
| Met 464 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 38239.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 380.1 | |
| All* | Total formula weight | 38619.9 |
