9FLC
Crystal structure of haspin (GSG2) in complex with MU1668
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Serine/threonine-protein kinase haspin | polymer | 357 | 40711.5 | 1 | UniProt (Q8TF76) Pfam (PF12330) | Homo sapiens (human) | Germ cell-specific gene 2 protein,H-haspin,Haploid germ cell-specific nuclear protein kinase |
| 2 | B (A) | 5-(1-methylpyrazol-3-yl)-3-pyridin-4-yl-thieno[3,2-b]pyridine | non-polymer | 292.4 | 1 | Chemie (A1IDA) | |||
| 3 | C (A) | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 1 | Chemie (MPD) | |||
| 4 | D (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | E (A) | water | water | 18.0 | 173 | Chemie (HOH) |
Sequence modifications
A: 465 - 798 (UniProt: Q8TF76)
| PDB | External Database | Details |
|---|---|---|
| Met 442 | - | initiating methionine |
| His 443 | - | expression tag |
| His 444 | - | expression tag |
| His 445 | - | expression tag |
| His 446 | - | expression tag |
| His 447 | - | expression tag |
| His 448 | - | expression tag |
| Ser 449 | - | expression tag |
| Ser 450 | - | expression tag |
| Gly 451 | - | expression tag |
| Val 452 | - | expression tag |
| Asp 453 | - | expression tag |
| Leu 454 | - | expression tag |
| Gly 455 | - | expression tag |
| Thr 456 | - | expression tag |
| Glu 457 | - | expression tag |
| Asn 458 | - | expression tag |
| Leu 459 | - | expression tag |
| Tyr 460 | - | expression tag |
| Phe 461 | - | expression tag |
| Gln 462 | - | expression tag |
| Ser 463 | - | expression tag |
| Met 464 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 40711.5 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 502.6 | |
| All* | Total formula weight | 41214.1 |
