9FL0

Discovery of a Series of Covalent, Cell Active Bfl-1 Inhibitors

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Bcl-2-related protein A1	polymer	152	17442.9	2	UniProt (Q16548) Pfam (PF00452)	Homo sapiens (human)	Bcl-2-like protein 5,Bcl2-L-5,Hemopoietic-specific early response protein,Protein BFL-1,Protein GRS
2	C, D (A, B)	~{N}-[(4-chlorophenyl)methyl]-~{N}-(4-fluorophenyl)prop-2-enamide	non-polymer		289.7	2	Chemie (A1IDG)
3	E, F (A, B)	water	water		18.0	53	Chemie (HOH)

Sequence modifications

A, B: 1 - 151 (UniProt: Q16548)

PDB	External Database	Details
Gly 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	34885.8
Non-Polymers*	Number of molecules	2
	Total formula weight	579.5
All*	Total formula weight	35465.2

*Water molecules are not included.