9FL0
Discovery of a Series of Covalent, Cell Active Bfl-1 Inhibitors
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Bcl-2-related protein A1 | polymer | 152 | 17442.9 | 2 | UniProt (Q16548) Pfam (PF00452) | Homo sapiens (human) | Bcl-2-like protein 5,Bcl2-L-5,Hemopoietic-specific early response protein,Protein BFL-1,Protein GRS |
| 2 | C, D (A, B) | ~{N}-[(4-chlorophenyl)methyl]-~{N}-(4-fluorophenyl)prop-2-enamide | non-polymer | 289.7 | 2 | Chemie (A1IDG) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 53 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 151 (UniProt: Q16548)
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 34885.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 579.5 | |
| All* | Total formula weight | 35465.2 |
