9FKP

Zebrafish Betaglycan Orphan Domain (zfBGo) in complex with TGF-b1 and extracellular domain of TGFBRII

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Transforming growth factor beta-1	polymer	112	12809.8	2	UniProt (P01137) Pfam (PF00019)	Homo sapiens (human)	TGF-beta-1
2	C, D (D, E)	TGF-beta receptor type-2	polymer	113	12926.8	2	UniProt (P37173) Pfam (PF08917)	Homo sapiens (human)	TGFR-2,TGF-beta type II receptor,Transforming growth factor-beta receptor type II,TGF-beta receptor type II,TbetaR-II
3	E (C)	Transforming growth factor beta receptor III	polymer	338	37727.0	1	UniProt (A0A0H3UK16) UniProt (by SIFTS) (E7FDB6)	Danio rerio (zebrafish)	Transforming growth factor beta receptor type 3 precursor

Sequence modifications

D, E: 42 - 153 (UniProt: P37173)

PDB	External Database	Details
Met 41	-	initiating methionine

C: 29 - 359 (UniProt: A0A0H3UK16)

PDB	External Database	Details
Gly 28	-	expression tag
Gly 150	Cys 150	engineered mutation
Gly 277	Cys 277	engineered mutation
His 360	-	expression tag
His 361	-	expression tag
His 362	-	expression tag
His 363	-	expression tag
His 364	-	expression tag
His 365	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	5
	Total formula weight	89200.2
All*	Total formula weight	89200.2

*Water molecules are not included.