9FKN

Human monocarboxylate transporter 8 bound to thyroxine

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Monocarboxylate transporter 8	polymer	521	57775.9	1	UniProt (P36021) Pfam (PF07690)	Homo sapiens (human)	MCT 8,Monocarboxylate transporter 7,MCT 7,Solute carrier family 16 member 2,X-linked PEST-containing transporter
2	B (B)	ALFA-tag nanobody	polymer	124	13599.2	1		Vicugna pacos
3	C (A)	3,5,3',5'-TETRAIODO-L-THYRONINE	non-polymer		776.9	1	Chemie (T44)

Sequence modifications

A: 2 - 498 (UniProt: P36021)

PDB	External Database	Details
Met -7	-	initiating methionine
Asp -6	-	expression tag
Tyr -5	-	expression tag
Lys -4	-	expression tag
Asp -3	-	expression tag
Asp -2	-	expression tag
Asp -1	-	expression tag
Asp 0	-	expression tag
Lys 1	-	expression tag
Ser 499	-	expression tag
Arg 500	-	expression tag
Leu 501	-	expression tag
Glu 502	-	expression tag
Glu 503	-	expression tag
Glu 504	-	expression tag
Leu 505	-	expression tag
Arg 506	-	expression tag
Arg 507	-	expression tag
Arg 508	-	expression tag
Leu 509	-	expression tag
Thr 510	-	expression tag
Glu 511	-	expression tag
Pro 512	-	expression tag
Ile 513	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	71375.1
Non-Polymers*	Number of molecules	1
	Total formula weight	776.9
All*	Total formula weight	72151.9

*Water molecules are not included.