9FJJ
Two PLK1 PBD proteins bound to CENP-U(39-114) phosphorylated at Thr78 and Thr98
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Serine/threonine-protein kinase PLK1 | polymer | 261 | 30006.2 | 2 | UniProt (P53350) Pfam (PF00659) | Homo sapiens (human) | Polo-like kinase 1,PLK-1,Serine/threonine-protein kinase 13,STPK13 |
| 2 | C (U) | Centromere protein U | polymer | 78 | 8665.9 | 1 | UniProt (Q71F23) | Homo sapiens (human) | CENP-U,Centromere protein of 50 kDa,CENP-50,Interphase centromere complex protein 24,KSHV latent nuclear antigen-interacting protein 1,MLF1-interacting protein,Polo-box-interacting protein 1 |
| 3 | D (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 4 | E (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | F, G, H (A, B, U) | water | water | 18.0 | 109 | Chemie (HOH) |
Sequence modifications
A, B: 345 - 603 (UniProt: P53350)
U: 39 - 114 (UniProt: Q71F23)
| PDB | External Database | Details |
|---|---|---|
| Gly 343 | - | expression tag |
| Ser 344 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 37 | - | expression tag |
| Ser 38 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 68678.3 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 198.2 | |
| All* | Total formula weight | 68876.5 |
