9FJG
Two PLK1 PBD proteins bound to CENP-U(58-114) phosphorylated at Thr98
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Serine/threonine-protein kinase PLK1 | polymer | 261 | 30006.2 | 2 | UniProt (P53350) Pfam (PF00659) | Homo sapiens (human) | Polo-like kinase 1,PLK-1,Serine/threonine-protein kinase 13,STPK13 |
| 2 | C (C) | Centromere protein U | polymer | 59 | 6493.7 | 1 | UniProt (Q71F23) | Homo sapiens (human) | CENP-U,Centromere protein of 50 kDa,CENP-50,Interphase centromere complex protein 24,KSHV latent nuclear antigen-interacting protein 1,MLF1-interacting protein,Polo-box-interacting protein 1 |
| 3 | D, F, I (A, B) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 3 | Chemie (PG4) | |||
| 4 | E (A) | CITRATE ANION | non-polymer | 189.1 | 1 | Chemie (FLC) | |||
| 5 | G, H (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 2 | Chemie (PEG) | |||
| 6 | J, K, L (A, B, C) | water | water | 18.0 | 105 | Chemie (HOH) |
Sequence modifications
A, B: 345 - 603 (UniProt: P53350)
C: 58 - 114 (UniProt: Q71F23)
| PDB | External Database | Details |
|---|---|---|
| Gly 343 | - | expression tag |
| Ser 344 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 56 | - | expression tag |
| Ser 57 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 66506.0 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 984.0 | |
| All* | Total formula weight | 67490.0 |
