9FIC
High-resolution X-ray structure of human PC1/3 (PCSK1) prodomain R77A,R80A,R81A triple-mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Neuroendocrine convertase 1 | polymer | 84 | 9551.6 | 1 | UniProt (P29120) Pfam (PF16470) | Homo sapiens (human) | NEC 1,Prohormone convertase 1,Proprotein convertase 1,PC1 |
| 2 | B, C, D (A) | SODIUM ION | non-polymer | 23.0 | 3 | Chemie (NA) | |||
| 3 | E (A) | water | water | 18.0 | 95 | Chemie (HOH) |
Sequence modifications
A: 28 - 110 (UniProt: P29120)
| PDB | External Database | Details |
|---|---|---|
| Gly 27 | - | expression tag |
| Ala 77 | Arg 77 | engineered mutation |
| Ala 80 | Arg 80 | engineered mutation |
| Ala 81 | Arg 81 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 9551.6 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 69.0 | |
| All* | Total formula weight | 9620.5 |
