9FGT
SARS-CoV-2 (B.1.1.529/Omicron variant) Spike protein in complex with the single chain fragment scFv76 (focused refinement)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | C | Spike glycoprotein,Fibritin | polymer | 1214 | 135255.2 | 1 | UniProt (P0DTC2) UniProt (P10104) Pfam (PF16451) Pfam (PF09408) Pfam (PF19209) Pfam (PF01601) In PDB | Severe acute respiratory syndrome coronavirus 2 | S glycoprotein,E2,Peplomer protein,Collar protein,Whisker antigen control protein |
2 | E | Single chain fragment scFv76 | polymer | 264 | 28040.9 | 1 | Homo sapiens | ||
3 | C | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) |
Sequence modifications
C: 16 - 1149 (UniProt: P0DTC2)
C: 1152 - 1178 (UniProt: P10104)
PDB | External Database | Details |
---|---|---|
Val 82 | Ala 67 | variant |
- | His 69 | deletion |
- | Val 70 | deletion |
- | Ser 71 | deletion |
- | Gly 72 | deletion |
- | Thr 73 | deletion |
- | Asn 74 | deletion |
- | Gly 75 | deletion |
- | Thr 76 | deletion |
Ser 84 | Lys 77 | variant |
Ile 102 | Thr 95 | variant |
Asp 149 | Gly 142 | variant |
Ile 218 | Asn 211 | variant |
Val 219 | Leu 212 | variant |
Pro 220 | Val 213 | variant |
Glu 221 | Arg 214 | variant |
- | Ser 247 | deletion |
- | Tyr 248 | deletion |
- | Leu 249 | deletion |
- | Thr 250 | deletion |
- | Pro 251 | deletion |
- | Gly 252 | deletion |
- | Asp 253 | deletion |
Asp 339 | Gly 339 | variant |
Leu 371 | Ser 371 | variant |
Pro 373 | Ser 373 | variant |
Phe 375 | Ser 375 | variant |
Asn 417 | Lys 417 | variant |
Lys 440 | Asn 440 | variant |
Ser 446 | Gly 446 | variant |
Asn 477 | Ser 477 | variant |
Lys 478 | Thr 478 | variant |
Ala 484 | Glu 484 | variant |
Arg 493 | Gln 493 | variant |
Ser 496 | Gly 496 | variant |
Arg 498 | Gln 498 | variant |
Tyr 501 | Asn 501 | variant |
His 505 | Tyr 505 | variant |
Lys 547 | Thr 547 | variant |
Gly 614 | Asp 614 | variant |
- | Pro 621 | deletion |
- | Val 622 | deletion |
- | Ala 623 | deletion |
- | Ile 624 | deletion |
- | His 625 | deletion |
- | Ala 626 | deletion |
- | Asp 627 | deletion |
- | Gln 628 | deletion |
- | Leu 629 | deletion |
- | Thr 630 | deletion |
- | Pro 631 | deletion |
- | Thr 632 | deletion |
- | Trp 633 | deletion |
- | Arg 634 | deletion |
- | Val 635 | deletion |
- | Tyr 636 | deletion |
- | Ser 637 | deletion |
- | Thr 638 | deletion |
- | Gly 639 | deletion |
- | Ser 640 | deletion |
Tyr 635 | His 655 | variant |
- | Gln 677 | deletion |
- | Thr 678 | deletion |
- | Asn 679 | deletion |
- | Ser 680 | deletion |
- | Pro 681 | deletion |
- | Arg 682 | deletion |
- | Arg 683 | deletion |
- | Ala 684 | deletion |
- | Arg 685 | deletion |
- | Ser 686 | deletion |
- | Val 687 | deletion |
- | Ala 688 | deletion |
Lys 732 | Asn 764 | variant |
Tyr 764 | Asp 796 | variant |
- | Pro 812 | deletion |
- | Leu 828 | deletion |
- | Ala 829 | deletion |
- | Asp 830 | deletion |
- | Ala 831 | deletion |
- | Gly 832 | deletion |
- | Phe 833 | deletion |
- | Ile 834 | deletion |
- | Lys 835 | deletion |
- | Gln 836 | deletion |
- | Tyr 837 | deletion |
- | Gly 838 | deletion |
- | Asp 839 | deletion |
- | Cys 840 | deletion |
- | Leu 841 | deletion |
- | Gly 842 | deletion |
- | Asp 843 | deletion |
- | Ile 844 | deletion |
- | Ala 845 | deletion |
- | Ala 846 | deletion |
- | Arg 847 | deletion |
- | Asp 848 | deletion |
- | Leu 849 | deletion |
- | Ile 850 | deletion |
- | Cys 851 | deletion |
- | Ala 852 | deletion |
- | Gln 853 | deletion |
Lys 797 | Asn 856 | variant |
His 895 | Gln 954 | variant |
Lys 910 | Asn 969 | variant |
Phe 922 | Leu 981 | variant |
Pro 927 | Lys 986 | engineered mutation |
Pro 928 | Val 987 | engineered mutation |
Gly 1150 | - | linker |
Ser 1151 | - | linker |
PDB | External Database | Details |
---|---|---|
Leu 1173 | Phe 479 | engineered mutation |
Gly 1179 | - | expression tag |
Arg 1180 | - | expression tag |
Ser 1181 | - | expression tag |
Leu 1182 | - | expression tag |
Glu 1183 | - | expression tag |
Val 1184 | - | expression tag |
Leu 1185 | - | expression tag |
Phe 1186 | - | expression tag |
Gln 1187 | - | expression tag |
Gly 1188 | - | expression tag |
Pro 1189 | - | expression tag |
Gly 1190 | - | expression tag |
His 1191 | - | expression tag |
His 1192 | - | expression tag |
His 1193 | - | expression tag |
His 1194 | - | expression tag |
His 1195 | - | expression tag |
His 1196 | - | expression tag |
His 1197 | - | expression tag |
His 1198 | - | expression tag |
Ser 1199 | - | expression tag |
Ala 1200 | - | expression tag |
Trp 1201 | - | expression tag |
Ser 1202 | - | expression tag |
His 1203 | - | expression tag |
Pro 1204 | - | expression tag |
Gln 1205 | - | expression tag |
Phe 1206 | - | expression tag |
Glu 1207 | - | expression tag |
Lys 1208 | - | expression tag |
Gly 1209 | - | expression tag |
Gly 1210 | - | expression tag |
Gly 1211 | - | expression tag |
Ser 1212 | - | expression tag |
Gly 1213 | - | expression tag |
Gly 1214 | - | expression tag |
Gly 1215 | - | expression tag |
Gly 1216 | - | expression tag |
Ser 1217 | - | expression tag |
Gly 1218 | - | expression tag |
Gly 1219 | - | expression tag |
Ser 1220 | - | expression tag |
Ala 1221 | - | expression tag |
Trp 1222 | - | expression tag |
Ser 1223 | - | expression tag |
His 1224 | - | expression tag |
Pro 1225 | - | expression tag |
Gln 1226 | - | expression tag |
Phe 1227 | - | expression tag |
Glu 1228 | - | expression tag |
Lys 1229 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 163296.1 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 221.2 | |
All* | Total formula weight | 163517.3 |