Loading
PDBj
MenuPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDBDonate
RCSB PDBPDBeBMRBAdv. SearchSearch help

9FEG

PARP15 in complex with a quinazolin-4-one inhibitor

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(B, A)
Protein mono-ADP-ribosyltransferase PARP15polymer20022967.82UniProt (Q460N3)
Pfam (PF00644)
Homo sapiens (human)ADP-ribosyltransferase diphtheria toxin-like 7,ARTD7,B-aggressive lymphoma protein 3,Poly [ADP-ribose] polymerase 15,PARP-15
2C
(B)
DIMETHYL SULFOXIDEnon-polymer78.11Chemie (DMS)
3D
(A)
(4S)-2-METHYL-2,4-PENTANEDIOLnon-polymer118.21Chemie (MPD)
4E
(A)
(2~{R})-~{N}-[2-(4-~{tert}-butylphenyl)-4-oxidanylidene-3~{H}-quinazolin-8-yl]-2,3-bis(oxidanyl)propanamidenon-polymer381.41Chemie (A1H44)
5F, G
(B, A)
waterwater18.0214Chemie (HOH)
Sequence modifications
B, A: 481 - 678 (UniProt: Q460N3)
PDBExternal DatabaseDetails
Ser 479-expression tag
Met 480-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight45935.6
Non-Polymers*Number of molecules3
Total formula weight577.7
All*Total formula weight46513.3
*Water molecules are not included.

246031

PDB entries from 2025-12-10

PDB statisticsPDBj update infoContact PDBjnumon