9FAR
CryoEM structure of gamma2 subunit of GABA(A)R in complex with GARLH4, the TMD of Neuroligin2 from a closed state, obtained by focused refinement
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (C) | Isoform 2 of Gamma-aminobutyric acid receptor subunit gamma-2 | polymer | 61 | 7923.6 | 1 | UniProt (P18507) | Homo sapiens (human) | GABA(A) receptor subunit gamma-2,GABAAR subunit gamma-2 |
| 2 | B (H) | Neuroligin-2 | polymer | 33 | 3614.1 | 1 | UniProt (Q8NFZ4) | Homo sapiens (human) | |
| 3 | C (L) | LHFPL tetraspan subfamily member 4 protein | polymer | 193 | 21366.2 | 1 | UniProt (Q7Z7J7) Pfam (PF10242) | Homo sapiens (human) | GABAA receptor regulatory Lhfpl4,Lipoma HMGIC fusion partner-like 4 protein |
| 4 | D (C) | PALMITIC ACID | non-polymer | 256.4 | 1 | Chemie (PLM) | |||
| 5 | E (C) | CHOLESTEROL | non-polymer | 386.7 | 1 | Chemie (CLR) | |||
| 6 | F (C) | DECANE | non-polymer | 142.3 | 1 | Chemie (D10) | |||
| 7 | G (L) | (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate | non-polymer | 749.0 | 1 | Chemie (PGW) | |||
| 8 | H (L) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) |
Sequence modifications
C: 369 - 428 (UniProt: P18507)
| PDB | External Database | Details |
|---|---|---|
| Gly 429 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 32903.9 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1569.8 | |
| All* | Total formula weight | 34473.8 |
