9FAN
CryoEM structure of gamma2 subunit of GABA(A)R in complex with GARLH4, the TMD of Neuroligin2 from desensitised state obtained by focused refinement
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (C) | Isoform 2 of Gamma-aminobutyric acid receptor subunit gamma-2 | polymer | 61 | 7923.6 | 1 | UniProt (P18507) | Homo sapiens (human) | GABA(A) receptor subunit gamma-2,GABAAR subunit gamma-2 |
| 2 | B (H) | Neuroligin-2 | polymer | 33 | 3614.1 | 1 | UniProt (Q8NFZ4) | Homo sapiens (human) | |
| 3 | C (L) | LHFPL tetraspan subfamily member 4 protein | polymer | 193 | 21366.2 | 1 | UniProt (Q7Z7J7) Pfam (PF10242) | Homo sapiens (human) | GABAA receptor regulatory Lhfpl4,Lipoma HMGIC fusion partner-like 4 protein |
| 4 | D (C) | PALMITIC ACID | non-polymer | 256.4 | 1 | Chemie (PLM) | |||
| 5 | E (C) | CHOLESTEROL | non-polymer | 386.7 | 1 | Chemie (CLR) PubChem (16219173) PubChem (16758052) PubChem (40477506) PubChem (40557614) PubChem (42579431) PubChem (42579432) PubChem (45044259) PubChem (49853509) PubChem (50990013) PubChem (176980071) PubChem (18640088) PubChem (52934537) PubChem (1715243) PubChem (1715244) PubChem (23423981) PubChem (44654663) PubChem (46937002) PubChem (56621683) PubChem (59274407) PubChem (68311425) PubChem (68311398) PubChem (143173313) PubChem (177156123) PubChem (5997) PubChem (57915018) PubChem (57939063) PubChem (58428240) PubChem (58445498) PubChem (58663286) PubChem (1551269) PubChem (90070115) PubChem (59450329) PubChem (59628412) PubChem (117965027) PubChem (6432564) PubChem (59965215) PubChem (71234641) PubChem (59993755) PubChem (60001463) PubChem (66634651) PubChem (6710666) PubChem (124146240) PubChem (7059399) PubChem (124897607) PubChem (124896959) PubChem (10861996) PubChem (68055877) PubChem (68166463) PubChem (68315613) PubChem (132837164) PubChem (70795838) PubChem (70797612) PubChem (70954610) PubChem (70957185) PubChem (71463909) PubChem (11834483) PubChem (11888915) PubChem (11888914) PubChem (304) PubChem (138967089) PubChem (139566851) PubChem (89951918) PubChem (90224410) PubChem (15939944) PubChem (91298236) PubChem (191463) PubChem (368063) PubChem (369319) PubChem (638019) PubChem (101624109) PubChem (1549081) PubChem (1553803) PubChem (171828367) PubChem (173516975) PubChem (124225449) PubChem (124429284) PubChem (5283629) PubChem (5284644) PubChem (5315842) PubChem (124909223) PubChem (124909224) PubChem (124909225) PubChem (6419195) PubChem (6994560) PubChem (130459183) PubChem (7055705) PubChem (7055706) PubChem (7059398) PubChem (7059400) PubChem (7059635) PubChem (7103033) PubChem (7182477) PubChem (7182478) PubChem (131992107) PubChem (9909206) PubChem (10045721) PubChem (71168115) PubChem (10134774) PubChem (10293553) PubChem (71173031) PubChem (11003580) PubChem (11025495) PubChem (11058155) PubChem (11463329) PubChem (11868624) PubChem (11868625) PubChem (11869366) PubChem (11869367) PubChem (11869368) PubChem (11869369) PubChem (12120344) PubChem (12156156) PubChem (139568882) PubChem (12303135) PubChem (12303148) PubChem (12303156) PubChem (12303159) PubChem (12303160) PubChem (142983773) PubChem (144054483) PubChem (144209461) PubChem (144331236) PubChem (144808354) PubChem (145053568) PubChem (145157652) PubChem (145215073) PubChem (145230478) PubChem (146320991) PubChem (147857230) PubChem (154993519) PubChem (158603858) PubChem (162906452) PubChem (162906453) PubChem (162906454) PubChem (162906455) PubChem (162906456) PubChem (162906457) PubChem (163255768) PubChem (163389210) PubChem (164665303) PubChem (166553771) PubChem (166712004) PubChem (170116175) PubChem (171764280) PubChem (171817101) PubChem (171817104) PubChem (174285573) | |||
| 6 | F (L) | DECANE | non-polymer | 142.3 | 1 | Chemie (D10) PubChem (15600) | |||
| 7 | G (L) | (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate | non-polymer | 749.0 | 1 | Chemie (PGW) | |||
| 8 | H (L) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) PubChem (312) |
Sequence modifications
C: 369 - 428 (UniProt: P18507)
| PDB | External Database | Details |
|---|---|---|
| Gly 429 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 32903.9 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1569.8 | |
| All* | Total formula weight | 34473.8 |
