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9FA3

Gcase in complex with small molecule inhibitor 1

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Lysosomal acid glucosylceramidasepolymer54661162.51UniProt (P04062)
Pfam (PF02055)
Pfam (PF17189)
Homo sapiens (human)Lysosomal acid GCase,Acid beta-glucosidase,Alglucerase,Beta-glucocerebrosidase,Beta-GC,Beta-glucosylceramidase 1,Cholesterol glucosyltransferase,SGTase,Cholesteryl-beta-glucosidase,D-glucosyl-N-acylsphingosine glucohydrolase,Glucosylceramidase beta 1,Imiglucerase,Lysosomal cholesterol glycosyltransferase,Lysosomal galactosylceramidase,Lysosomal glycosylceramidase
2B
(B)
2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranosebranched424.41In PDB
GlyTouCan (G42666HT)
3C, D
(A)
2-acetamido-2-deoxy-beta-D-glucopyranosenon-polymer221.22Chemie (NAG)
4E, F
(A)
POTASSIUM IONnon-polymer39.12Chemie (K)
5G
(A)
SULFATE IONnon-polymer96.11Chemie (SO4)
6H
(A)
~{N}-(cyclopropylmethyl)benzenesulfonamidenon-polymer211.31Chemie (A1IBC)
7I
(A)
waterwater18.0430Chemie (HOH)
Sequence modifications
A: 1 - 536 (UniProt: P04062)
PDBExternal DatabaseDetails
His 537-expression tag
His 538-expression tag
His 539-expression tag
His 540-expression tag
His 541-expression tag
His 542-expression tag
His 543-expression tag
His 544-expression tag
His 545-expression tag
His 546-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight61162.5
BranchedNumber of molecules1
Total formula weight424.4
Non-Polymers*Number of molecules6
Total formula weight828.0
All*Total formula weight62414.9
*Water molecules are not included.

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