9F99

Crystal structure of MUS81-EME1 bound by compound 10.

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E, G	Crossover junction endonuclease MUS81	polymer	308	34159.9	4	UniProt (Q96NY9) Pfam (PF02732) Pfam (PF21292) In PDB	Homo sapiens (human)
2	B, D, F, H	Crossover junction endonuclease EME1	polymer	326	36144.2	4	UniProt (Q96AY2) Pfam (PF02732) Pfam (PF21292) In PDB	Homo sapiens (human)	MMS4 homolog,hMMS4
3	A, C, E, G	2-(4-chlorophenyl)-5-oxidanyl-6-oxidanylidene-1H-pyrimidine-4-carboxylic acid	non-polymer		266.6	4	Chemie (A1IA5)
4	A, C, E, G	MAGNESIUM ION	non-polymer		24.3	8	Chemie (MG)

Sequence modifications

A, C, E, G: 246 - 551 (UniProt: Q96NY9)

PDB	External Database	Details
Gly 244	-	expression tag
Ser 245	-	expression tag

B, D, F, H: 246 - 570 (UniProt: Q96AY2)

PDB	External Database	Details
Gly 245	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	281216.3
Non-Polymers*	Number of molecules	12
	Total formula weight	1261.0
All*	Total formula weight	282477.3

*Water molecules are not included.