9F6X
Human transforming growth factor b type I receptor in complex with kinase inhibitor SB505124
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | TGF-beta receptor type-1 | polymer | 303 | 34565.7 | 1 | UniProt (P36897) Pfam (PF00069) | Homo sapiens | TGFR-1,Activin A receptor type II-like protein kinase of 53kD,Activin receptor-like kinase 5,ALK-5,ALK5,Serine/threonine-protein kinase receptor R4,SKR4,TGF-beta type I receptor,Transforming growth factor-beta receptor type I,TGF-beta receptor type I,TbetaR-I |
| 2 | B (A) | 2-[5-(1,3-benzodioxol-5-yl)-2-~{tert}-butyl-1~{H}-imidazol-4-yl]-6-methyl-pyridine | non-polymer | 335.4 | 1 | Chemie (A1IAZ) | |||
| 3 | C, D (A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 4 | E (A) | water | water | 18.0 | 93 | Chemie (HOH) |
Sequence modifications
A: 1 - 301 (UniProt: P36897)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Gly 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34565.7 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 519.6 | |
| All* | Total formula weight | 35085.3 |
