9F2N
Structure of human carbonic anhydrase XII complexed with 3-(cyclooctylamino)-2,6-difluoro-4-((3-hydroxypropyl)sulfonyl)-5-(piperidin-1-yl)benzenesulfonamide
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Carbonic anhydrase 12 | polymer | 263 | 29917.3 | 2 | UniProt (O43570) Pfam (PF00194) | Homo sapiens (human) | Carbonate dehydratase XII,Carbonic anhydrase XII,CA-XII,Tumor antigen HOM-RCC-3.1.3 |
| 2 | C, F (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | D, G, H, I, J (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 5 | Chemie (EDO) | |||
| 4 | E, K (A, B) | 3-(cyclooctylamino)-2,6-difluoro-4-((3-hydroxypropyl)sulfonyl)-5-(piperidin-1-yl)benzenesulfonamide | non-polymer | 523.7 | 2 | Chemie (A1H9A) | |||
| 5 | L, M (A, B) | water | water | 18.0 | 475 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 263 (UniProt: O43570)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 59834.6 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1488.5 | |
| All* | Total formula weight | 61323.1 |
