9F2E
Carbonic anhydrase II variant with bound iron complex in space group C2 (ArPase)
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Carbonic anhydrase 2 | polymer | 260 | 29283.9 | 1 | UniProt (P00918) Pfam (PF00194) | Homo sapiens (human) | Carbonate dehydratase II,Carbonic anhydrase C,CAC,Carbonic anhydrase II,CA-II,Cyanamide hydratase CA2 |
| 2 | B (A) | 4,4,7,10,10-pentamethyl-3,6,8,11-tetrakis(oxidanylidene)-N-[2-(4-sulfamoylphenyl)ethyl]-2,5,7,9,12-pentazabicyclo[11.4.0]heptadeca-1(13),14,16-triene-15-carboxamide containing iron | non-polymer | 639.5 | 1 | Chemie (A1H9O) | |||
| 3 | C, E (A) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 4 | D (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 5 | F (A) | water | water | 18.0 | 182 | Chemie (HOH) |
Sequence modifications
A: 1 - 260 (UniProt: P00918)
| PDB | External Database | Details |
|---|---|---|
| Ala 2 | Ser 2 | engineered mutation |
| Thr 65 | Ala 65 | engineered mutation |
| His 100 | Leu 100 | engineered mutation |
| Leu 153 | Lys 153 | engineered mutation |
| Ser 205 | Cys 205 | engineered mutation |
| Ser 223 | Leu 223 | engineered mutation |
| Pro 239 | Leu 239 | engineered mutation |
| Thr 247 | Ala 247 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 29283.9 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 832.3 | |
| All* | Total formula weight | 30116.2 |
