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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

9F1C

Mammalian quaternary complex of a translating 80S ribosome, NAC, MetAP1 and NatA/E

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AHmRNApolymer3543.31Oryctolagus cuniculus (rabbit)
2Bb60S ribosomal protein L29polymer24526721.71UniProt (G1SGR6)
Pfam (PF01779)
In PDB		Oryctolagus cuniculus (rabbit)
3B75S rRNApolymer12038691.91GenBank (4CXE_4)Oryctolagus cuniculus (rabbit)
4ATP-site tRNApolymer7615209.51Oryctolagus cuniculus (rabbit)
5ArSmall ribosomal subunit protein uS13polymer15117670.61UniProt (G1TPG3)
Pfam (PF00416)
In PDB		Oryctolagus cuniculus (rabbit)40S ribosomal protein S18
6B85.8S rRNApolymer15850809.01GenBank (GBCN01009604.1)Oryctolagus cuniculus (rabbit)
7BU60S ribosomal protein L22polymer12814756.91UniProt (G1TSG1)
Pfam (PF01776)
In PDB		Oryctolagus cuniculus (rabbit)
8As40S ribosomal protein S19polymer14516104.61UniProt (G1TN62)
Pfam (PF01090)
In PDB		Oryctolagus cuniculus (rabbit)
9BALarge ribosomal subunit protein uL2polymer25728103.91UniProt (G1TT27)
Pfam (PF00181)
Pfam (PF03947)
In PDB		Oryctolagus cuniculus (rabbit)60S ribosomal protein L8
10BVRibosomal protein L23polymer14014892.51UniProt (G1T6D1)
Pfam (PF00238)
In PDB		Oryctolagus cuniculus (rabbit)
11AtSmall ribosomal subunit protein uS10polymer11913398.81UniProt (G1SIZ2)
Pfam (PF00338)
In PDB		Oryctolagus cuniculus (rabbit)40S ribosomal protein S20
12BBRibosomal protein L3polymer40346121.01UniProt (G1TL06)
Pfam (PF00297)
In PDB		Oryctolagus cuniculus (rabbit)
13BXRibosomal_L23eN domain-containing proteinpolymer15617768.21UniProt (G1SE76)
Pfam (PF03939)
Pfam (PF00276)
In PDB		Oryctolagus cuniculus (rabbit)uL23
14AuSmall ribosomal subunit protein eS21polymer839181.41UniProt (G1TM82)
Pfam (PF01249)
In PDB		Oryctolagus cuniculus (rabbit)40S ribosomal protein S21
15BCLarge ribosomal subunit protein uL4polymer41246299.71UniProt (G1SVW5)
Pfam (PF00573)
Pfam (PF14374)
In PDB		Oryctolagus cuniculus (rabbit)60S ribosomal protein L4
16BPLarge ribosomal subunit protein uL22polymer18421444.21UniProt (G1SCJ6)
Pfam (PF00237)
In PDB		Oryctolagus cuniculus (rabbit)60S ribosomal protein L17
17BZ60S ribosomal protein L27polymer13615835.81UniProt (G1TXF6)
Pfam (PF00467)
Pfam (PF01777)
In PDB		Oryctolagus cuniculus (rabbit)
18Aw40S ribosomal protein S23polymer14315860.71UniProt (G1SZ47)
Pfam (PF00164)
In PDB		Oryctolagus cuniculus (rabbit)
19BE60S ribosomal protein L6polymer29133028.31UniProt (G1SKF7)
Pfam (PF03868)
Pfam (PF01159)
In PDB		Oryctolagus cuniculus (rabbit)
20B528S rRNApolymer48081557519.51GenBank (GBCN01009604.1)Oryctolagus cuniculus (rabbit)
21BQLarge ribosomal subunit protein eL18polymer18821699.71Oryctolagus cuniculus (rabbit)
22Ba60S ribosomal protein L27apolymer14816635.61UniProt (G1SNY0)
Pfam (PF00828)
In PDB		Oryctolagus cuniculus (rabbit)
23Ax40S ribosomal protein S24polymer13015107.91UniProt (G1T3D8)
Pfam (PF01282)
In PDB		Oryctolagus cuniculus (rabbit)
24BFRibosomal Protein uL30polymer24729201.81UniProt (G1TUB1)
Pfam (PF08079)
Pfam (PF00327)
In PDB		Oryctolagus cuniculus (rabbit)
25BYRibosomal protein L26polymer14517303.41UniProt (G1SQH0)
Pfam (PF16906)
Pfam (PF00467)
In PDB		Oryctolagus cuniculus (rabbit)
26BWRibosomal protein L24polymer15717825.11UniProt (G1SE28)
Pfam (PF01246)
In PDB		Oryctolagus cuniculus (rabbit)eL24
27AZSmall ribosomal subunit protein uS2polymer29432838.81UniProt (G1TLT8)
Pfam (PF00318)
Pfam (PF16122)
In PDB		Oryctolagus cuniculus (rabbit)37 kDa laminin receptor precursor,37LRP,37/67 kDa laminin receptor,LRP/LR,67 kDa laminin receptor,67LR,Laminin receptor 1,LamR,Laminin-binding protein precursor p40,LBP/p40
28Ay40S ribosomal protein S25polymer12413645.01UniProt (G1TDB3)
Pfam (PF03297)
In PDB		Oryctolagus cuniculus (rabbit)
29BG60S ribosomal protein L7apolymer26630061.81Oryctolagus cuniculus (rabbit)
30AvRibosomal protein S15apolymer13014865.61UniProt (G1TG89)
Pfam (PF00410)
In PDB		Oryctolagus cuniculus (rabbit)
31BRRibosomal protein L19polymer19623535.31UniProt (G1TJR3)
Pfam (PF01280)
In PDB		Oryctolagus cuniculus (rabbit)
32Aa40S ribosomal protein S3apolymer26430002.11UniProt (G1SS70)
Pfam (PF01015)
In PDB		Oryctolagus cuniculus (rabbit)RPS3A
33Az60S ribosomal protein L41polymer253473.51UniProt (A0A087WNH4)
Pfam (PF05162)
In PDB		Oryctolagus cuniculus (rabbit)
34BH60S ribosomal protein L9polymer19221871.41UniProt (G1SWI6)
Pfam (PF00347)
In PDB		Oryctolagus cuniculus (rabbit)
35BSLarge ribosomal subunit protein eL20polymer17620749.41UniProt (G1TTY7)
Pfam (PF01775)
In PDB		Oryctolagus cuniculus (rabbit)60S ribosomal protein L18a
36AbSmall ribosomal subunit protein uS5polymer29331285.41Oryctolagus cuniculus (rabbit)
37Bc60S ribosomal protein L30polymer11512807.11UniProt (G1TDL2)
Pfam (PF01248)
In PDB		Oryctolagus cuniculus (rabbit)eL30
38BI60S ribosomal protein L10polymer21424643.11UniProt (B7NZQ2)
Pfam (PF00252)
In PDB		Oryctolagus cuniculus (rabbit)Ribosomal protein L10
39BLarge ribosomal subunit protein uL18polymer29734481.81UniProt (G1SZF4)
Pfam (PF17144)
Pfam (PF14204)
In PDB		Oryctolagus cuniculus (rabbit)uL18
40EAMethionine aminopeptidase 1polymer38643274.21UniProt (P53582)
Pfam (PF15801)
Pfam (PF00557)
In PDB		Homo sapiens (human)MAP 1,MetAP 1,Peptidase M 1
41Ac40S ribosomal protein S3polymer28131146.61UniProt (G1TNM3)
Pfam (PF07650)
Pfam (PF00189)
In PDB		Oryctolagus cuniculus (rabbit)uS3
42Bd60S ribosomal protein L31polymer12514494.91UniProt (G1SHG0)
Pfam (PF01198)
In PDB		Oryctolagus cuniculus (rabbit)eL31
43BJ60S ribosomal protein L11polymer17820288.51UniProt (G1TUB8)
Pfam (PF00281)
Pfam (PF00673)
In PDB		Oryctolagus cuniculus (rabbit)
44CtNascent polypeptide-associated complex subunit alphapolymer23825857.51UniProt (Q13765)
Pfam (PF01849)
Pfam (PF19026)
In PDB		Homo sapiens (human)NAC-alpha,Alpha-NAC
45Ad40S ribosomal protein S4polymer26329654.91UniProt (G1TK17)
Pfam (PF08071)
Pfam (PF00900)
Pfam (PF00467)
Pfam (PF16121)
In PDB		Oryctolagus cuniculus (rabbit)
46BeRibosomal protein L32polymer13515898.91UniProt (A0AAA9WVN6)
In PDB		Oryctolagus cuniculus (rabbit)
47BKNascent chainpolymer322741.41Oryctolagus cuniculus (rabbit)
48CuTranscription factor BTF3polymer16217724.01UniProt (P20290)
Pfam (PF01849)
In PDB		Homo sapiens (human)Nascent polypeptide-associated complex subunit beta,NAC-beta,RNA polymerase B transcription factor 3
49AeRibosomal protein S5polymer20422913.51UniProt (G1TFM5)
Pfam (PF00177)
In PDB		Oryctolagus cuniculus (rabbit)
50Bf60S ribosomal protein L35apolymer11012580.81UniProt (G1SF08)
Pfam (PF01247)
In PDB		Oryctolagus cuniculus (rabbit)eL33
51BLLarge ribosomal subunit protein eL13polymer21124331.71UniProt (G1TKB3)
Pfam (PF01294)
In PDB		Oryctolagus cuniculus (rabbit)60S ribosomal protein L13
52DAGlutathione S-transferase class-mu 26 kDa isozyme,N-alpha-acetyltransferase 50polymer40346529.71UniProt (P08515)
UniProt (Q9GZZ1)
Pfam (PF14497)
Pfam (PF00583)
Pfam (PF02798)
In PDB		Schistosoma japonicumGST 26,Sj26 antigen,SjGST,hNaa50p,N-acetyltransferase 13,N-acetyltransferase 5,hNAT5,N-acetyltransferase san homolog,hSAN,N-epsilon-acetyltransferase 50,NatE catalytic subunit
53Af40S ribosomal protein S6polymer24928751.91UniProt (G1TM55)
Pfam (PF01092)
In PDB		Oryctolagus cuniculus (rabbit)
54Bg60S ribosomal protein L34polymer11713326.11UniProt (G1TXG5)
Pfam (PF01199)
In PDB		Oryctolagus cuniculus (rabbit)
55BM60S ribosomal protein L14polymer21823870.51UniProt (G1SZ12)
Pfam (PF01929)
In PDB		Oryctolagus cuniculus (rabbit)
56DBN-alpha-acetyltransferase 15, NatA auxiliary subunitpolymer915106506.31UniProt (Q9BXJ9)
Pfam (PF13181)
Pfam (PF12569)
In PDB		Homo sapiens (human)Gastric cancer antigen Ga19,N-terminal acetyltransferase,NMDA receptor-regulated protein 1,Protein tubedown-1,Tbdn100
57Ag40S ribosomal protein S7polymer43247356.21UniProt (G1SVB0)
In PDB		Oryctolagus cuniculus (rabbit)
58Bh60S ribosomal protein L35polymer12314566.61UniProt (G1SIT5)
Pfam (PF00831)
In PDB		Oryctolagus cuniculus (rabbit)uL29
59BNRibosomal protein L15polymer20424207.31UniProt (G1T0C1)
Pfam (PF00827)
In PDB		Oryctolagus cuniculus (rabbit)
60DCN-alpha-acetyltransferase 10polymer23526479.61UniProt (P41227)
Pfam (PF00583)
In PDB		Homo sapiens (human)N-terminal acetyltransferase complex ARD1 subunit homolog A,hARD1,NatA catalytic subunit Naa10
61Ah40S ribosomal protein S8polymer20824263.41UniProt (G1TJW1)
Pfam (PF01201)
In PDB		Oryctolagus cuniculus (rabbit)
62Bi60S ribosomal protein L36polymer10512263.81UniProt (G1TTQ5)
Pfam (PF01158)
In PDB		Oryctolagus cuniculus (rabbit)
63BOLarge ribosomal subunit protein uL13polymer20323533.31UniProt (G1TVS8)
In PDB		Oryctolagus cuniculus (rabbit)60S ribosomal protein L13a
64A218S rRNApolymer1870603928.31GenBank (GBCT01000564.1)Oryctolagus cuniculus (rabbit)
65Ai40S ribosomal protein S9polymer19422641.61UniProt (B7NZS8)
Pfam (PF00163)
Pfam (PF01479)
In PDB		Oryctolagus cuniculus (rabbit)
66BjRibosomal protein L37polymer9711111.01UniProt (U3KPD5)
Pfam (PF01907)
In PDB		Oryctolagus cuniculus (rabbit)
67AA40S ribosomal protein S27polymer849480.21UniProt (G1TZ76)
Pfam (PF01667)
In PDB		Oryctolagus cuniculus (rabbit)
68AjS10_plectin domain-containing proteinpolymer16518933.81UniProt (G1TPV3)
Pfam (PF03501)
In PDB		Oryctolagus cuniculus (rabbit)eS10
69Bk60S ribosomal protein L38polymer708238.91UniProt (G1U001)
Pfam (PF01781)
In PDB		Oryctolagus cuniculus (rabbit)eL38
70AB40S ribosomal protein S28polymer697855.11UniProt (G1TIB4)
Pfam (PF01200)
In PDB		Oryctolagus cuniculus (rabbit)
71Ak40S ribosomal protein S11polymer15818468.81UniProt (G1TRM4)
Pfam (PF16205)
Pfam (PF00366)
In PDB		Oryctolagus cuniculus (rabbit)
72Bl60S ribosomal protein L39-likepolymer516455.81UniProt (G1TTN1)
Pfam (PF00832)
In PDB		Oryctolagus cuniculus (rabbit)eL39
73ACRibosomal protein S27apolymer15618004.01UniProt (G1SK22)
Pfam (PF00240)
Pfam (PF01599)
In PDB		Oryctolagus cuniculus (rabbit)
74Al40S ribosomal protein S12polymer13214539.01UniProt (G1SFR8)
Pfam (PF01248)
In PDB		Oryctolagus cuniculus (rabbit)
75BmLarge ribosomal subunit protein eL40polymer12814800.51UniProt (P0DXC2)
In PDB		Oryctolagus cuniculus (rabbit)60S ribosomal protein L40
76AD40S ribosomal protein S30polymer13314498.91UniProt (G1T8A2)
Pfam (PF00240)
Pfam (PF04758)
In PDB		Oryctolagus cuniculus (rabbit)
77Am40S ribosomal protein S13polymer15117259.41UniProt (G1SP51)
Pfam (PF08069)
Pfam (PF00312)
In PDB		Oryctolagus cuniculus (rabbit)uS15
78BoLarge ribosomal subunit protein eL42polymer10612490.01UniProt (A0AAA9WX15)
In PDB		Oryctolagus cuniculus (rabbit)
79AESmall ribosomal subunit protein eS26polymer11513047.51Oryctolagus cuniculus (rabbit)
80AnSmall ribosomal subunit protein uS11polymer15116302.81UniProt (A0AAA9WYR1)
In PDB		Oryctolagus cuniculus (rabbit)
81Bp60S ribosomal protein L37apolymer9210299.41UniProt (G1SY53)
Pfam (PF01780)
In PDB		Oryctolagus cuniculus (rabbit)eL43
82AFSmall ribosomal subunit protein RACK1polymer31735115.71UniProt (G1SJB4)
Pfam (PF00400)
In PDB		Oryctolagus cuniculus (rabbit)RACK1
83Ao40S ribosomal protein uS19polymer14517049.21UniProt (G1U0Q2)
Pfam (PF00203)
In PDB		Oryctolagus cuniculus (rabbit)
84BrLarge ribosomal subunit protein eL28polymer13615713.51UniProt (G1U7L1)
Pfam (PF01778)
In PDB		Oryctolagus cuniculus (rabbit)60S ribosomal protein L28
85AG40S ribosomal protein S29polymer566690.81UniProt (G1U7M4)
Pfam (PF00253)
In PDB		Oryctolagus cuniculus (rabbit)uS14
86ApSmall ribosomal subunit protein uS9polymer17219213.51UniProt (G1SGX4)
Pfam (PF00380)
In PDB		Oryctolagus cuniculus (rabbit)uS9
87Bs60S acidic ribosomal protein P0polymer31834380.51UniProt (G1SPK4)
Pfam (PF00466)
Pfam (PF17777)
Pfam (PF00428)
In PDB		Oryctolagus cuniculus (rabbit)uL10
88BT60S ribosomal protein L21polymer16018610.01UniProt (G1SHQ2)
Pfam (PF01157)
In PDB		Oryctolagus cuniculus (rabbit)eL21
89Aq40S ribosomal protein eS17polymer13515552.11UniProt (G1TU13)
Pfam (PF00833)
In PDB		Oryctolagus cuniculus (rabbit)
90Bt60S ribosomal protein L12polymer16517847.61UniProt (G1SMR7)
Pfam (PF03946)
Pfam (PF00298)
In PDB		Oryctolagus cuniculus (rabbit)
91A2, B7, B5, BB, BQ...UNKNOWN ATOM OR IONnon-polymer277Chemie (UNX)
92A2, BV, B5, BB, B7...MAGNESIUM IONnon-polymer24.3420Chemie (MG)
93B7GUANOSINE-5'-TRIPHOSPHATEnon-polymer523.21Chemie (GTP)
94B5, A2SPERMIDINEnon-polymer145.230Chemie (SPD)
95A2, B5SPERMINEnon-polymer202.33Chemie (SPM)
96Bj, AC, Bm, Bo, AE...ZINC IONnon-polymer65.48Chemie (ZN)
97DBINOSITOL HEXAKISPHOSPHATEnon-polymer660.01Chemie (IHP)
98waterwater18.02117Chemie (HOH)
Sequence modifications
BU: 1 - 128 (UniProt: G1TSG1)
PDBExternal DatabaseDetails
Gly 32Arg 32variant
Ala 36Glu 36variant
Phe 39Ser 39variant
Gly 54Arg 54variant
Arg 97His 97variant
As: 1 - 145 (UniProt: G1TN62)
PDBExternal DatabaseDetails
Gly 119Trp 119variant
Asn 142Lys 142variant
B5: 1 - 4808 (GenBank: GBCN01009604.1)
PDBExternal DatabaseDetails
Uy1 3550U 5943conflict
BF: 1 - 247 (UniProt: G1TUB1)
PDBExternal DatabaseDetails
Arg 61Gly 61variant
Arg 93Gly 93variant
Met 131Val 131variant
Ile 153Val 153variant
BR: 1 - 196 (UniProt: G1TJR3)
PDBExternal DatabaseDetails
Arg 38Cys 38variant
Arg 64Gln 64variant
Thr 94Lys 94variant
B: 1 - 297 (UniProt: G1SZF4)
PDBExternal DatabaseDetails
Ser 176Gly 176variant
Arg 248Gln 248variant
EA: 1 - 386 (UniProt: P53582)
PDBExternal DatabaseDetails
Asn 220Asp 220engineered mutation
Ct: 1 - 215 (UniProt: Q13765)
PDBExternal DatabaseDetails
Met -22-initiating methionine
Gly -21-expression tag
Ser -20-expression tag
Ser -19-expression tag
His -18-expression tag
His -17-expression tag
His -16-expression tag
His -15-expression tag
His -14-expression tag
His -13-expression tag
Ser -12-expression tag
Ser -11-expression tag
Gly -10-expression tag
Leu -9-expression tag
Glu -8-expression tag
Val -7-expression tag
Leu -6-expression tag
Phe -5-expression tag
Gln -4-expression tag
Gly -3-expression tag
Pro -2-expression tag
Ser -1-expression tag
Gly 0-expression tag
Ad: 1 - 263 (UniProt: G1TK17)
PDBExternal DatabaseDetails
Gly 25Ser 25variant
Arg 51Lys 51variant
Thr 78Ala 78variant
Val 156Met 156variant
BL: 1 - 211 (UniProt: G1TKB3)
PDBExternal DatabaseDetails
Arg 74His 74variant
Arg 190His 190variant
DA: -233 - -16 (UniProt: P08515)
PDBExternal DatabaseDetails
Gly -15-linker
Ser -14-linker
Gly -13-linker
Ser -12-linker
Gly -11-linker
Ser -10-linker
Glu -9-linker
Asn -8-linker
Leu -7-linker
Tyr -6-linker
Phe -5-linker
Gln -4-linker
Gly -3-linker
Ala -2-linker
Met -1-linker
Val 0-linker
DA: 1 - 169 (UniProt: Q9GZZ1)
DB: 1 - 866 (UniProt: Q9BXJ9)
PDBExternal DatabaseDetails
Met -48-initiating methionine
Gly -47-expression tag
Ser -46-expression tag
Ser -45-expression tag
His -44-expression tag
His -43-expression tag
His -42-expression tag
His -41-expression tag
His -40-expression tag
His -39-expression tag
Ser -38-expression tag
Ser -37-expression tag
Gly -36-expression tag
Leu -35-expression tag
Val -34-expression tag
Pro -33-expression tag
Arg -32-expression tag
Gly -31-expression tag
Ser -30-expression tag
His -29-expression tag
Met -28-expression tag
Ala -27-expression tag
Ser -26-expression tag
Met -25-expression tag
Thr -24-expression tag
Gly -23-expression tag
Gly -22-expression tag
Gln -21-expression tag
Gln -20-expression tag
Met -19-expression tag
Gly -18-expression tag
Arg -17-expression tag
Ala -16-expression tag
Arg -15-expression tag
Gly -14-expression tag
Ile -13-expression tag
Gln -12-expression tag
Arg -11-expression tag
Pro -10-expression tag
Thr -9-expression tag
Ser -8-expression tag
Thr -7-expression tag
Ser -6-expression tag
Ser -5-expression tag
Leu -4-expression tag
Val -3-expression tag
Ala -2-expression tag
Ala -1-expression tag
Ala 0-expression tag
DC: 1 - 235 (UniProt: P41227)
PDBExternal DatabaseDetails
Gln 24Glu 24engineered mutation
Phe 26Tyr 26engineered mutation
Ah: 1 - 208 (UniProt: G1TJW1)
PDBExternal DatabaseDetails
Arg 47Gly 47variant
A2: 1 - 1870 (GenBank: GBCT01000564.1)
PDBExternal DatabaseDetails
B8n 1249C 3623conflict
4ac 1338C 3712conflict
4ac 1843C 4217conflict
Bk: 1 - 70 (UniProt: G1U001)
PDBExternal DatabaseDetails
Lys 24Asn 24variant
An: 1 - 151 (UniProt: A0AAA9WYR1)
PDBExternal DatabaseDetails
Ias 138Asp 155conflict
Br: 2 - 137 (UniProt: G1U7L1)
PDBExternal DatabaseDetails
Arg 103His 103conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains90
Total formula weight4083084.6
Non-Polymers*Number of molecules740
Total formula weight16879.0
All*Total formula weight4099963.5
*Water molecules are not included.

225681

PDB entries from 2024-10-02

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