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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

9F1B

Mammalian ternary complex of a translating 80S ribosome, NAC and NatA/E

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(BP)		Large ribosomal subunit protein uL22polymer18421444.21UniProt (G1SCJ6)
Pfam (PF00237)		Oryctolagus cuniculus (rabbit)60S ribosomal protein L17
2B
(Aq)		40S ribosomal protein eS17polymer13515552.11UniProt (G1TU13)
Pfam (PF00833)		Oryctolagus cuniculus (rabbit)
3C
(Bo)		Large ribosomal subunit protein eL42polymer10612490.01UniProt (A0AAA9WX15)Oryctolagus cuniculus (rabbit)
4D
(AT)		P-site tRNApolymer7615209.51Oryctolagus cuniculus (rabbit)
5E
(Ar)		Small ribosomal subunit protein uS13polymer15117670.61UniProt (G1TPG3)
Pfam (PF00416)		Oryctolagus cuniculus (rabbit)40S ribosomal protein S18
6F
(Cu)		Transcription factor BTF3polymer16217724.01UniProt (P20290)
Pfam (PF01849)		Homo sapiens (human)Nascent polypeptide-associated complex subunit beta,NAC-beta,RNA polymerase B transcription factor 3
7G
(BL)		Large ribosomal subunit protein eL13polymer21124331.71UniProt (G1TKB3)
Pfam (PF01294)		Oryctolagus cuniculus (rabbit)60S ribosomal protein L13
8H
(BX)		Ribosomal_L23eN domain-containing proteinpolymer15617768.21UniProt (G1SE76)
Pfam (PF03939)
Pfam (PF00276)		Oryctolagus cuniculus (rabbit)uL23
9I
(Bp)		60S ribosomal protein L37apolymer9210299.41UniProt (G1SY53)
Pfam (PF01780)		Oryctolagus cuniculus (rabbit)eL43
10J
(BQ)		Large ribosomal subunit protein eL18polymer18821699.71Oryctolagus cuniculus (rabbit)
11K
(As)		40S ribosomal protein S19polymer14516104.61UniProt (G1TN62)
Pfam (PF01090)		Oryctolagus cuniculus (rabbit)
12L
(Br)		Large ribosomal subunit protein eL28polymer13615713.51UniProt (G1U7L1)
Pfam (PF01778)		Oryctolagus cuniculus (rabbit)60S ribosomal protein L28
13M
(BR)		Ribosomal protein L19polymer19623535.31UniProt (G1TJR3)
Pfam (PF01280)		Oryctolagus cuniculus (rabbit)
14N
(At)		Small ribosomal subunit protein uS10polymer11913398.81UniProt (G1SIZ2)
Pfam (PF00338)		Oryctolagus cuniculus (rabbit)40S ribosomal protein S20
15O
(Bs)		60S acidic ribosomal protein P0polymer31834380.51UniProt (G1SPK4)
Pfam (PF00466)
Pfam (PF17777)
Pfam (PF00428)		Oryctolagus cuniculus (rabbit)uL10
16P
(BG)		60S ribosomal protein L7apolymer26630061.81Oryctolagus cuniculus (rabbit)
17Q
(BU)		60S ribosomal protein L22polymer12814756.91UniProt (G1TSG1)
Pfam (PF01776)		Oryctolagus cuniculus (rabbit)
18R
(Av)		Ribosomal protein S15apolymer13014865.61UniProt (G1TG89)
Pfam (PF00410)		Oryctolagus cuniculus (rabbit)
19S
(DB)		N-alpha-acetyltransferase 15, NatA auxiliary subunitpolymer915106506.31UniProt (Q9BXJ9)
Pfam (PF13181)
Pfam (PF12569)		Homo sapiens (human)Gastric cancer antigen Ga19,N-terminal acetyltransferase,NMDA receptor-regulated protein 1,Protein tubedown-1,Tbdn100
20T
(Ct)		Nascent polypeptide-associated complex subunit alphapolymer23825857.51UniProt (Q13765)
Pfam (PF01849)
Pfam (PF19026)		Homo sapiens (human)NAC-alpha,Alpha-NAC
21U
(BH)		60S ribosomal protein L9polymer19221871.41UniProt (G1SWI6)
Pfam (PF00347)		Oryctolagus cuniculus (rabbit)
22V
(BV)		Ribosomal protein L23polymer14014892.51UniProt (G1T6D1)
Pfam (PF00238)		Oryctolagus cuniculus (rabbit)
23W
(Aw)		40S ribosomal protein S23polymer14315860.71UniProt (G1SZ47)
Pfam (PF00164)		Oryctolagus cuniculus (rabbit)
24X
(B5)		28S rRNApolymer48081557519.51GenBank (GBCN01009604.1)Oryctolagus cuniculus (rabbit)
25Y
(BT)		60S ribosomal protein L21polymer16018610.01UniProt (G1SHQ2)
Pfam (PF01157)		Oryctolagus cuniculus (rabbit)eL21
26Z
(BI)		60S ribosomal protein L10polymer21424643.11UniProt (B7NZQ2)
Pfam (PF00252)		Oryctolagus cuniculus (rabbit)Ribosomal protein L10
27AA
(BW)		Ribosomal protein L24polymer15717825.11UniProt (G1SE28)
Pfam (PF01246)		Oryctolagus cuniculus (rabbit)eL24
28BA
(Ax)		40S ribosomal protein S24polymer13015107.91UniProt (G1T3D8)
Pfam (PF01282)		Oryctolagus cuniculus (rabbit)
29CA
(B7)		5S rRNApolymer11938346.71GenBank (GBCM01014045.1)Oryctolagus cuniculus (rabbit)
30DA
(Au)		Small ribosomal subunit protein eS21polymer839181.41UniProt (G1TM82)
Pfam (PF01249)		Oryctolagus cuniculus (rabbit)40S ribosomal protein S21
31EA
(BJ)		60S ribosomal protein L11polymer17820288.51UniProt (G1TUB8)
Pfam (PF00281)
Pfam (PF00673)		Oryctolagus cuniculus (rabbit)
32FA
(AZ)		Small ribosomal subunit protein uS2polymer29432838.81UniProt (G1TLT8)
Pfam (PF00318)
Pfam (PF16122)		Oryctolagus cuniculus (rabbit)37 kDa laminin receptor precursor,37LRP,37/67 kDa laminin receptor,LRP/LR,67 kDa laminin receptor,67LR,Laminin receptor 1,LamR,Laminin-binding protein precursor p40,LBP/p40
33GA
(Ay)		40S ribosomal protein S25polymer12413645.01UniProt (G1TDB3)
Pfam (PF03297)		Oryctolagus cuniculus (rabbit)
34HA
(B8)		5.8S rRNApolymer15850809.01GenBank (GBCN01009604.1)Oryctolagus cuniculus
35IA
(BK)		Nascent chainpolymer292486.11Oryctolagus cuniculus (rabbit)
36JA
(Aa)		40S ribosomal protein S3apolymer26430002.11UniProt (G1SS70)
Pfam (PF01015)		Oryctolagus cuniculus (rabbit)RPS3A
37KA
(Az)		60S ribosomal protein L41polymer253473.51UniProt (A0A087WNH4)
Pfam (PF05162)		Oryctolagus cuniculus (rabbit)
38LA
(BA)		Large ribosomal subunit protein uL2polymer25728103.91UniProt (G1TT27)
Pfam (PF00181)
Pfam (PF03947)		Oryctolagus cuniculus (rabbit)60S ribosomal protein L8
39MA
(Bt)		60S ribosomal protein L12polymer16517847.61UniProt (G1SMR7)
Pfam (PF03946)
Pfam (PF00298)		Oryctolagus cuniculus (rabbit)
40NA
(BM)		60S ribosomal protein L14polymer21823870.51UniProt (G1SZ12)
Pfam (PF01929)		Oryctolagus cuniculus (rabbit)
41OA
(Ab)		40S ribosomal protein S2polymer29331285.41Oryctolagus cuniculus (rabbit)
42PA
(BY)		Ribosomal protein L26polymer14517303.41UniProt (G1SQH0)
Pfam (PF16906)
Pfam (PF00467)		Oryctolagus cuniculus (rabbit)
43QA
(BB)		Ribosomal protein L3polymer40346121.01UniProt (G1TL06)
Pfam (PF00297)		Oryctolagus cuniculus (rabbit)
44RA
(BS)		Large ribosomal subunit protein eL20polymer17620749.41UniProt (G1TTY7)
Pfam (PF01775)		Oryctolagus cuniculus (rabbit)60S ribosomal protein L18a
45SA
(Ac)		40S ribosomal protein S3polymer28131146.61UniProt (G1TNM3)
Pfam (PF07650)
Pfam (PF00189)		Oryctolagus cuniculus (rabbit)uS3
46TA
(BZ)		60S ribosomal protein L27polymer13615835.81UniProt (G1TXF6)
Pfam (PF00467)
Pfam (PF01777)		Oryctolagus cuniculus (rabbit)
47UA
(BC)		Large ribosomal subunit protein uL4polymer41246299.71UniProt (G1SVW5)
Pfam (PF00573)
Pfam (PF14374)		Oryctolagus cuniculus (rabbit)60S ribosomal protein L4
48VA
(BN)		Ribosomal protein L15polymer20424207.31UniProt (G1T0C1)
Pfam (PF00827)		Oryctolagus cuniculus (rabbit)
49WA
(Ad)		40S ribosomal protein S4polymer26329654.91UniProt (G1TK17)
Pfam (PF08071)
Pfam (PF00900)
Pfam (PF00467)
Pfam (PF16121)		Oryctolagus cuniculus (rabbit)
50XA
(Ba)		60S ribosomal protein L27apolymer14816635.61UniProt (G1SNY0)
Pfam (PF00828)		Oryctolagus cuniculus (rabbit)
51YA
(B)		Large ribosomal subunit protein uL18polymer29734481.81UniProt (G1SZF4)
Pfam (PF17144)
Pfam (PF14204)		Oryctolagus cuniculus (rabbit)uL18
52ZA
(BO)		Large ribosomal subunit protein uL13polymer20323533.31UniProt (G1TVS8)Oryctolagus cuniculus (rabbit)60S ribosomal protein L13a
53AB
(Ae)		Ribosomal protein S5polymer20422913.51UniProt (G1TFM5)
Pfam (PF00177)		Oryctolagus cuniculus (rabbit)
54BB
(Bb)		60S ribosomal protein L29polymer24526721.71UniProt (G1SGR6)
Pfam (PF01779)		Oryctolagus cuniculus (rabbit)
55CB
(BE)		60S ribosomal protein L6polymer29133028.31UniProt (G1SKF7)
Pfam (PF03868)
Pfam (PF01159)		Oryctolagus cuniculus (rabbit)
56DB
(DA)		Glutathione S-transferase class-mu 26 kDa isozyme,N-alpha-acetyltransferase 50polymer40346529.71UniProt (P08515)
UniProt (Q9GZZ1)
Pfam (PF02798)
Pfam (PF14497)
Pfam (PF00583)		Schistosoma japonicumGST 26,Sj26 antigen,SjGST,hNaa50p,N-acetyltransferase 13,N-acetyltransferase 5,hNAT5,N-acetyltransferase san homolog,hSAN,N-epsilon-acetyltransferase 50,NatE catalytic subunit
57EB
(Af)		40S ribosomal protein S6polymer24928751.91UniProt (G1TM55)
Pfam (PF01092)		Oryctolagus cuniculus (rabbit)
58FB
(Bc)		60S ribosomal protein L30polymer11512807.11UniProt (G1TDL2)
Pfam (PF01248)		Oryctolagus cuniculus (rabbit)eL30
59GB
(BF)		Ribosomal Protein uL30polymer24729201.81UniProt (G1TUB1)
Pfam (PF08079)
Pfam (PF00327)		Oryctolagus cuniculus (rabbit)
60HB
(DC)		N-alpha-acetyltransferase 10polymer23526479.61UniProt (P41227)
Pfam (PF00583)		Homo sapiens (human)N-terminal acetyltransferase complex ARD1 subunit homolog A,hARD1,NatA catalytic subunit Naa10
61IB
(Ag)		40S ribosomal protein S7polymer43247356.21UniProt (G1SVB0)Oryctolagus cuniculus (rabbit)
62JB
(Bd)		60S ribosomal protein L31polymer12514494.91UniProt (G1SHG0)
Pfam (PF01198)		Oryctolagus cuniculus (rabbit)eL31
63KB
(A2)		18S rRNApolymer1870603928.31GenBank (GBCT01000564.1)Oryctolagus cuniculus (rabbit)
64LB
(Ah)		40S ribosomal protein S8polymer20824263.41UniProt (G1TJW1)
Pfam (PF01201)		Oryctolagus cuniculus (rabbit)
65MB
(Be)		Ribosomal protein L32polymer13515898.91UniProt (G1U6S0)
Pfam (PF01655)		Oryctolagus cuniculus (rabbit)
66NB
(AA)		40S ribosomal protein S27polymer849480.21UniProt (G1TZ76)
Pfam (PF01667)		Oryctolagus cuniculus (rabbit)
67OB
(Ai)		40S ribosomal protein S9polymer19422641.61UniProt (B7NZS8)
Pfam (PF00163)
Pfam (PF01479)		Oryctolagus cuniculus (rabbit)
68PB
(Bf)		60S ribosomal protein L35apolymer11012580.81UniProt (G1SF08)
Pfam (PF01247)		Oryctolagus cuniculus (rabbit)eL33
69QB
(AB)		40S ribosomal protein S28polymer697855.11UniProt (G1TIB4)
Pfam (PF01200)		Oryctolagus cuniculus (rabbit)
70RB
(Aj)		S10_plectin domain-containing proteinpolymer16518933.81UniProt (G1TPV3)
Pfam (PF03501)		Oryctolagus cuniculus (rabbit)eS10
71SB
(Bg)		Large ribosomal subunit protein eL34polymer11513125.81UniProt (G1TXG5)
Pfam (PF01199)		Oryctolagus cuniculus (rabbit)60S ribosomal protein L34
72TB
(AC)		Ribosomal protein S27apolymer15618004.01UniProt (G1SK22)
Pfam (PF00240)
Pfam (PF01599)		Oryctolagus cuniculus (rabbit)
73UB
(Ak)		40S ribosomal protein S11polymer15818468.81UniProt (G1TRM4)
Pfam (PF16205)
Pfam (PF00366)		Oryctolagus cuniculus (rabbit)
74VB
(Bh)		60S ribosomal protein L35polymer12314566.61UniProt (G1SIT5)
Pfam (PF00831)		Oryctolagus cuniculus (rabbit)uL29
75WB
(AD)		40S ribosomal protein S30polymer13314498.91UniProt (G1T8A2)
Pfam (PF00240)
Pfam (PF04758)		Oryctolagus cuniculus (rabbit)
76XB
(Al)		40S ribosomal protein S12polymer13214539.01UniProt (G1SFR8)
Pfam (PF01248)		Oryctolagus cuniculus (rabbit)
77YB
(Bi)		60S ribosomal protein L36polymer10512263.81UniProt (G1TTQ5)
Pfam (PF01158)		Oryctolagus cuniculus (rabbit)
78ZB
(AE)		Small ribosomal subunit protein eS26polymer11513047.51Oryctolagus cuniculus (rabbit)
79AC
(Am)		40S ribosomal protein S13polymer15117259.41UniProt (G1SP51)
Pfam (PF08069)
Pfam (PF00312)		Oryctolagus cuniculus (rabbit)uS15
80BC
(Bj)		Ribosomal protein L37polymer9711111.01UniProt (U3KPD5)
Pfam (PF01907)		Oryctolagus cuniculus (rabbit)
81CC
(AF)		Small ribosomal subunit protein RACK1polymer31735115.71UniProt (G1SJB4)
Pfam (PF00400)		Oryctolagus cuniculus (rabbit)RACK1
82DC
(An)		Small ribosomal subunit protein uS11polymer15116302.81UniProt (A0AAA9WYR1)Oryctolagus cuniculus (rabbit)
83EC
(Bk)		60S ribosomal protein L38polymer708238.91UniProt (G1U001)
Pfam (PF01781)		Oryctolagus cuniculus (rabbit)eL38
84FC
(AG)		40S ribosomal protein S29polymer566690.81UniProt (G1U7M4)
Pfam (PF00253)		Oryctolagus cuniculus (rabbit)uS14
85GC
(Ao)		40S ribosomal protein uS19polymer14517049.21UniProt (G1U0Q2)
Pfam (PF00203)		Oryctolagus cuniculus (rabbit)
86HC
(Bl)		60S ribosomal protein L39-likepolymer516455.81UniProt (G1TTN1)
Pfam (PF00832)		Oryctolagus cuniculus (rabbit)eL39
87IC
(AH)		mRNApolymer3543.31Oryctolagus cuniculus (rabbit)
88JC
(Ap)		Small ribosomal subunit protein uS9polymer17219213.51UniProt (G1SGX4)
Pfam (PF00380)		Oryctolagus cuniculus (rabbit)uS9
89KC
(Bm)		Ubiquitin-ribosomal protein eL40 fusion proteinpolymer12814800.51UniProt (P0DXC2)Oryctolagus cuniculus (rabbit)Ubiquitin A-52 residue ribosomal protein fusion product 1
90AAA, ACA, AD, ADA, AE...
(A2, Ct, B5, B8, BV...)		MAGNESIUM IONnon-polymer24.3420Chemie (MG)
91MC, OFA, PFA, RFA, SFA...
(Bo, Bg, AC, AE, Bj...)		ZINC IONnon-polymer65.48Chemie (ZN)
92ABA, AEA, AF, AFA, AJ...
(A2, B5, B7, B8, BH...)		UNKNOWN ATOM OR IONnon-polymer145.2306Chemie (UNX)
93ZC
(DB)		INOSITOL HEXAKISPHOSPHATEnon-polymer660.01Chemie (IHP)
94BR, CK, DBA, DU, EF...
(B5, A2)		SPERMIDINEnon-polymer145.230Chemie (SPD)
95HCA, HJ, QH
(A2, B5)		SPERMINEnon-polymer202.33Chemie (SPM)
96PX
(B7)		GUANOSINE-5'-TRIPHOSPHATEnon-polymer523.21Chemie (GTP)
97AGA, AHA, BGA, BHA, CGA...
(BP, BO, Bo, Af, AT...)		waterwater18.02116Chemie (HOH)
Sequence modifications
BL: 1 - 211 (UniProt: G1TKB3)
PDBExternal DatabaseDetails
Arg 74His 74variant
Arg 190His 190variant
As: 1 - 145 (UniProt: G1TN62)
PDBExternal DatabaseDetails
Gly 119Trp 119variant
Asn 142Lys 142variant
Br: 2 - 137 (UniProt: G1U7L1)
PDBExternal DatabaseDetails
Arg 103His 103conflict
BR: 1 - 196 (UniProt: G1TJR3)
PDBExternal DatabaseDetails
Arg 38Cys 38variant
Arg 64Gln 64variant
Thr 94Lys 94variant
BU: 1 - 128 (UniProt: G1TSG1)
PDBExternal DatabaseDetails
Gly 32Arg 32variant
Ala 36Glu 36variant
Phe 39Ser 39variant
Gly 54Arg 54variant
Arg 97His 97variant
DB: 1 - 866 (UniProt: Q9BXJ9)
PDBExternal DatabaseDetails
Met -48-initiating methionine
Gly -47-expression tag
Ser -46-expression tag
Ser -45-expression tag
His -44-expression tag
His -43-expression tag
His -42-expression tag
His -41-expression tag
His -40-expression tag
His -39-expression tag
Ser -38-expression tag
Ser -37-expression tag
Gly -36-expression tag
Leu -35-expression tag
Val -34-expression tag
Pro -33-expression tag
Arg -32-expression tag
Gly -31-expression tag
Ser -30-expression tag
His -29-expression tag
Met -28-expression tag
Ala -27-expression tag
Ser -26-expression tag
Met -25-expression tag
Thr -24-expression tag
Gly -23-expression tag
Gly -22-expression tag
Gln -21-expression tag
Gln -20-expression tag
Met -19-expression tag
Gly -18-expression tag
Arg -17-expression tag
Ala -16-expression tag
Arg -15-expression tag
Gly -14-expression tag
Ile -13-expression tag
Gln -12-expression tag
Arg -11-expression tag
Pro -10-expression tag
Thr -9-expression tag
Ser -8-expression tag
Thr -7-expression tag
Ser -6-expression tag
Ser -5-expression tag
Leu -4-expression tag
Val -3-expression tag
Ala -2-expression tag
Ala -1-expression tag
Ala 0-expression tag
Ct: 1 - 215 (UniProt: Q13765)
PDBExternal DatabaseDetails
Met -22-initiating methionine
Gly -21-expression tag
Ser -20-expression tag
Ser -19-expression tag
His -18-expression tag
His -17-expression tag
His -16-expression tag
His -15-expression tag
His -14-expression tag
His -13-expression tag
Ser -12-expression tag
Ser -11-expression tag
Gly -10-expression tag
Leu -9-expression tag
Glu -8-expression tag
Val -7-expression tag
Leu -6-expression tag
Phe -5-expression tag
Gln -4-expression tag
Gly -3-expression tag
Pro -2-expression tag
Ser -1-expression tag
Gly 0-expression tag
B5: 1 - 4808 (GenBank: GBCN01009604.1)
PDBExternal DatabaseDetails
Uy1 3550U 5943conflict
Ad: 1 - 263 (UniProt: G1TK17)
PDBExternal DatabaseDetails
Gly 25Ser 25variant
Arg 51Lys 51variant
Thr 78Ala 78variant
Val 156Met 156variant
B: 1 - 297 (UniProt: G1SZF4)
PDBExternal DatabaseDetails
Ser 176Gly 176variant
Arg 248Gln 248variant
DA: -233 - -16 (UniProt: P08515)
PDBExternal DatabaseDetails
Gly -15-linker
Ser -14-linker
Gly -13-linker
Ser -12-linker
Gly -11-linker
Ser -10-linker
Glu -9-linker
Asn -8-linker
Leu -7-linker
Tyr -6-linker
Phe -5-linker
Gln -4-linker
Gly -3-linker
Ala -2-linker
Met -1-linker
Val 0-linker
DA: 1 - 169 (UniProt: Q9GZZ1)
BF: 1 - 247 (UniProt: G1TUB1)
PDBExternal DatabaseDetails
Arg 61Gly 61variant
Arg 93Gly 93variant
Met 131Val 131variant
Ile 153Val 153variant
DC: 1 - 235 (UniProt: P41227)
PDBExternal DatabaseDetails
Gln 24Glu 24engineered mutation
Phe 26Tyr 26engineered mutation
A2: 1 - 1870 (GenBank: GBCT01000564.1)
PDBExternal DatabaseDetails
B8n 1249C 3623conflict
4ac 1338C 3712conflict
4ac 1843C 4217conflict
Ah: 1 - 208 (UniProt: G1TJW1)
PDBExternal DatabaseDetails
Arg 47Gly 47variant
Be: 1 - 135 (UniProt: G1U6S0)
PDBExternal DatabaseDetails
Arg 22Cys 22variant
Arg 75His 75variant
An: 1 - 151 (UniProt: A0AAA9WYR1)
PDBExternal DatabaseDetails
Ias 138Asp 155conflict
Bk: 1 - 70 (UniProt: G1U001)
PDBExternal DatabaseDetails
Lys 24Asn 24variant
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains89
Total formula weight4039009.6
Non-Polymers*Number of molecules769
Total formula weight61324.3
All*Total formula weight4100333.8
*Water molecules are not included.

244349

PDB entries from 2025-11-05

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