9EZA
Interleukin-31 Receptor D1D2 in complex with Nemolizumab derived scFv
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Nemolizumab scFv | polymer | 260 | 27660.2 | 2 | Mus musculus | ||
| 2 | B, D (B, D) | Interleukin-31 receptor subunit alpha | polymer | 261 | 30266.3 | 2 | UniProt (Q8NI17) Pfam (PF09240) | Homo sapiens (human) | IL-31 receptor subunit alpha,IL-31R subunit alpha,IL-31R-alpha,IL-31RA,Cytokine receptor-like 3,GLM-R,hGLM-R,Gp130-like monocyte receptor,Gp130-like receptor,ZcytoR17 |
| 3 | E (E) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 4 | F, G, H, I (B, D) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) PubChem (24139) | |||
| 5 | J (D) | BES buffer | non-polymer | 213.3 | 1 | Chemie (A1H79) PubChem (73243) | |||
| 6 | K, L, M, N (A, B, C, D) | water | water | 18.0 | 242 | Chemie (HOH) |
Sequence modifications
B, D: 2 - 224 (UniProt: Q8NI17)
| PDB | External Database | Details |
|---|---|---|
| Gly 225 | - | expression tag |
| Thr 226 | - | expression tag |
| Ser 227 | - | expression tag |
| Asp 228 | - | expression tag |
| Glu 229 | - | expression tag |
| Val 230 | - | expression tag |
| Asp 231 | - | expression tag |
| Gly 232 | - | expression tag |
| Gly 233 | - | expression tag |
| Ser 234 | - | expression tag |
| Gly 235 | - | expression tag |
| Gly 236 | - | expression tag |
| Ser 237 | - | expression tag |
| Gly 238 | - | expression tag |
| Leu 239 | - | expression tag |
| Asn 240 | - | expression tag |
| Asp 241 | - | expression tag |
| Ile 242 | - | expression tag |
| Phe 243 | - | expression tag |
| Glu 244 | - | expression tag |
| Ala 245 | - | expression tag |
| Gln 246 | - | expression tag |
| Lys 247 | - | expression tag |
| Ile 248 | - | expression tag |
| Glu 249 | - | expression tag |
| Trp 250 | - | expression tag |
| His 251 | - | expression tag |
| Glu 252 | - | expression tag |
| Gly 253 | - | expression tag |
| Arg 254 | - | expression tag |
| Thr 255 | - | expression tag |
| Lys 256 | - | expression tag |
| His 257 | - | expression tag |
| His 258 | - | expression tag |
| His 259 | - | expression tag |
| His 260 | - | expression tag |
| His 261 | - | expression tag |
| His 262 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 115852.9 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 424.4 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1098.1 | |
| All* | Total formula weight | 117375.4 |
