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9EYW

Human PRMT5 in complex with AZ compound 21

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1AProtein arginine N-methyltransferase 5, N-terminally processedpolymer63772766.71UniProt (O14744)
Pfam (PF17285)
Pfam (PF05185)
Pfam (PF17286)
In PDB
Homo sapiens (human)
2BMethylosome protein WDR77polymer34236757.21UniProt (Q9BQA1)
Pfam (PF00400)
In PDB
Homo sapiens (human)Androgen receptor cofactor p44,Methylosome protein 50,MEP-50,WD repeat-containing protein 77,p44/Mep50
3A(3~{S})-2-[(5-azanyl-1~{H}-pyrrolo[3,2-b]pyridin-2-yl)methyl]-6-fluoranyl-1'-[(4-fluorophenyl)methyl]spiro[isoindole-3,3'-pyrrolidine]-1,2'-dionenon-polymer473.51Chemie (A1H8B)
4A5'-DEOXY-5'-METHYLTHIOADENOSINEnon-polymer297.31Chemie (MTA)
5ASULFATE IONnon-polymer96.11Chemie (SO4)
6waterwater18.061Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight109523.9
Non-Polymers*Number of molecules3
Total formula weight866.9
All*Total formula weight110390.8
*Water molecules are not included.

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PDB entries from 2024-10-16

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