9EXU
Complex of a mutant of the SARS-CoV-2 main protease Mpro with the nsp4/5 substrate peptide (cocrystallization).
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Non-structural protein 7 | polymer | 306 | 33726.4 | 2 | UniProt (P0DTD1) Pfam (PF05409) | Severe acute respiratory syndrome coronavirus 2 | nsp7 |
| 2 | C, D (C, D) | THR-SER-ALA-VAL-LEU-GLN-SER-GLY-PHE-ARG-LYS | polymer | 11 | 1237.4 | 2 | UniProt (by SIFTS) (P0DTD1) | Severe acute respiratory syndrome coronavirus 2 | |
| 3 | E, F, G, H (A, B, C, D) | water | water | 18.0 | 331 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 306 (UniProt: P0DTD1)
| PDB | External Database | Details |
|---|---|---|
| Ala 41 | His 3304 | conflict |
| Ala 145 | Cys 3408 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 69927.6 | |
| All* | Total formula weight | 69927.6 |
