9EW8
Discovery of a Series of Covalent, Cell Active Bfl-1 Inhibitors
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Bcl-2-related protein A1 | polymer | 152 | 17442.9 | 1 | UniProt (Q16548) Pfam (PF00452) | Homo sapiens (human) | Bcl-2-like protein 5,Bcl2-L-5,Hemopoietic-specific early response protein,Protein BFL-1,Protein GRS |
| 2 | B (A) | 1-[(2R)-2-phenylpyrrolidin-1-yl]propan-1-one | non-polymer | 203.3 | 1 | Chemie (A1H7Q) | |||
| 3 | C (A) | water | water | 18.0 | 75 | Chemie (HOH) |
Sequence modifications
A: 1 - 151 (UniProt: Q16548)
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 17442.9 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 203.3 | |
| All* | Total formula weight | 17646.2 |
